Category: Featured

As cannabis legislation continues to evolve, new consumers are entering the market daily. With cannabis consumption comes the question: what product do I use and what is the best way to consume it? While our care team is here to help you with product suggestions specific to your ailment, this blog is here to help you with cannabis devices for smoking. Quality is what we value – from the support you receive, to the product you use, to the device you administer your product with – we only want to recommend the best for you. 

 

This is why we have created this short resource guide for cannabis consumption and devices – because the quality of your product matters, so do the accessories for your cannabis. 

 

First let’s talk about consuming your cannabis. What is the best way? 

 

Cannabinoid therapy truly requires an individualized approach. How you choose to consume may be best determined by the ailment you are seeking relief from as there may be pros and cons to every method. 

 

If you choose to consume flower – where do you start on a device? At Realm of Caring, we value companies who also value education, transparency, excellent customer service, and overall quality. 

 

Not sure what a bubble cap is? No need to worry, CannaDevices has you covered. From handpipes to nectar straws, CannaDevices creates beautiful, safe, handmade glass devices and educates you. For example, they explain why it is important to understand where your product was manufactured. Imported glass may contain toxic chemicals and/or paint that mimics colored glass. As well, glass products may have “glass dust” left behind from where holes were drilled, this is potential residue you do not want to inhale. 

 

If you’re seeking a more simple, cost effective option look for ethically sourced and environmentally-friendly rolling papers. The Consumer put together a list of the healthiest paper alternatives that are clean and sustainable, meaning no bleaches or harmful additives. 

 

How do you store your cannabis? 

 

A dad concerned that his kiddos might find or get into his medicine asked the same question. This is why he created Stashlogix, cases and bags with smell proof technology. They serve responsible consumers looking for high quality thoughtful, secure, and discreet products. In addition to trapping and absorbing the odor of your cannabis, most products have an integrated 3-digit combination zipper lock and are shipped to you straight from Colorado.

 

How do you keep your cannabis devices clean? 

 

Leaff carries quality, elegant pieces to fit your lifestyle to speak to the uniqueness of each cannabis consumer. They also educate on best practices like how to keep your devices clean to increase the lifespan of your accessories. If you are going to invest in a tourmaline quartz pipe, you’ll want to make sure you can treasure it for years to come. 

 

Sanitary devices like the Moose Labs MouthPeace have also been devised to dramatically decrease the spread and amount of bacteria on your devices. Made from biodegradable and recycled materials, they also help to enhance your experience by removing resins, contaminants, and tar without reducing the airflow. 

 

If you are new to the cannabis space, it doesn’t have to be intimidating. Our care team is here to support you on your journey. Reach out by emailing info@realmofcaring.org or calling (719) 347-5400, option 1. 

 

Image courtesy of CannaDevices

Endometriosis is a severe and often debilitating chronic inflammatory condition. It affects approximately 10% of reproductive aged people (190 million) with a female
reproductive system on a global scale (World Health Organization, 2021). This condition is defined by endometrial glands, stroma, or other cells found growing outside of the uterus, in locations such as on the ovaries or on the pelvic peritoneum.

 

Endometriosis is characterized by pain (often severe), infertility, psychological distress and fatigue, dysmenorrhea (menstrual cramps), dyschezia (constipation), dyspareunia (painful intercourse), dysuria (painful urination), and chronic non-menstrual pelvic pain. In addition, comorbidities often include bladder pain or irritable bowel syndrome.

 

Over 95% of cases with deep infiltrated endometriosis report suffering from extreme levels of pain. Furthermore, symptoms can begin as early as adolescence and have a negative impact on the developing brain.

 

Since a definitive diagnosis requires surgery, many go undiagnosed for some time after symptoms begin. With many variables and pathways involved, the exact cause of endometriosis is mostly unknown. The general belief is that a combination of hormonal, immunological, and neurological factors contribute to the disease’s development. There is no cure available today, only symptom management.

 

The endocannabinoid system (ECS) plays an important role in the mechanisms involved in endometriosis development, disease maintenance and pain. The ECS is also involved in the immune response, and demonstrates antiproliferative and antifibrotic effects.

 

CB1 receptors are highly expressed in the uterus, whereas both CB1 and CB2 receptors are highly expressed in human oocytes. One of the main enzymes of the endocannabinoid system, Anandamide (AEA), is found in the fluids of the female reproductive tract and ovaries. AEA plays an important role in several key functions including folliculogenesis, preovulatory follicle maturation, oocyte maturation, and ovulation.

 

In terms of current scientific research regarding cannabis and endometriosis, there is a fair number of studies available with promising results. Currently, there are only two trials exploring the use of cannabinoids as a treatment for endometriosis pain, NCT03875261 and NCT04527003 (National Institute of Health, 2022).

 

The current therapeutic options available for endometriosis patients include diet changes, surgery, and pain relieving or anti-inflammatory medications. Unfortunately, these options are associated with severe unwanted side effects, high rates of recurrence and only seem to provide limited efficacy.

 

Cannabinoids are commonly used by chronic pain patients and many people with endometriosis are turning to cannabis for relief. Varied expression of cannabinoid receptors, enzymes, and endocannabinoids will affect how a person responds to treatment.

 

Cannabis has the potential to serve as a therapeutic option for those seeking a more natural treatment, with significantly less side effects than current pharmaceutical therapies. While the ECS has great potential to act as a promising target for treatment of endometriosis, it is important to note that the biphasic effects of the cannabinoid D9-THC may result in undesired outcomes. Lower concentrations of this cannabinoid may increase cancer cell proliferation, but at higher concentrations D9-THC has shown to decrease cancer cell proliferation. This presents as one of the biggest issues for people attempting to determine proper dosage from home.

 

As always, we recommend speaking with a licensed medical professional before starting a new cannabis regime. To learn more about the potential benefits of cannabinoid therapy, please reach out to our care team!

 

 

By: Jazmin Oliver / Cannabis Science Consultants

 

 

Citations 

 

1. Andrieu, T, Chicca, A. Pellegata, D., Bersinger, N., Imboden, S., Nirgianakis, K., Gertsch, J., Mueller, M. Association of endocannabinoids with pain in endometriosis, PAIN: January 2022 – Volume 163 – Issue 1 – p 193-203. doi: 10.1097/j.pain.0000000000002333
2. Bouaziz J, Seidman DS, Soriano D. The Clinical Significance of Endocannabinoids in Endometriosis Pain Management. Cannabis Cannabinoid Res. 2017 Apr 1;2(1):72-80. doi: 10.1089/can.2016.0035. 
3. Sanchez, P. Vigano, A. Mugione, P. Panina-Bordignon, M. Candiani. The molecular connections between the cannabinoid system and endometriosis, Molecular Human Reproduction, Volume 18, Issue 12, December 2012, Pages 563–571. https://doi.org/10.1093/molehr/gas037

4. Saunders P., Horne A., Endometriosis: Etiology, pathobiology, and therapeutic prospects, Cell, Volume 184, Issue 11, 2021, Pages 2807-2824, ISSN 0092-8674, https://doi.org/10.1016/j.cell.2021.04.041. 
5. https://clinicaltrials.gov
6. https://www.who.int/news-room/fact-sheets/detail/endometriosis

 

 

Disclaimer

 

The Realm of Caring Foundation specifically invokes the first amendment rights of freedom of speech and of the press without prejudice. These statements have not been evaluated by the food and drug administration. The products discussed are not intended to diagnose, cure, prevent or treat any disease. Realm of Caring always recommends when and wherever possible that licensed local healthcare professionals be consulted.

 

The Realm of Caring Foundation is an independent nonprofit with its own governing board. We do not produce or sell cannabinoid products, nor do we receive funds from the sale of company’s products we support.

“Picture a room with 1,000 TVs with each TV showing something different. Now try and concentrate on just one TV without getting distracted.”  –Damian DaViking Aird

 

 

Attention deficit hyperactivity disorder (ADHD) is the most frequent neuro-developmental disorder among children and often continues into adolescence and adulthood. It’s most often characterized by an inability to sit still, properly manage behavior, and difficulty focusing. Presently, there are a number of medications prescribed to help better manage symptoms of the disorder, with those searching for alternative options looking to cannabis for relief. 

 

Many adults with ADHD choose to self-treat with cannabis, claiming that it helps some of their more severe symptoms (e.g., agitation, irritability, lack of control) while also carrying fewer side effects to prescription medications. 

 

Can Cannabis Help With ADHD?

 

The current research available gives somewhat of a mixed answer to whether or not cannabinoid therapy can be used as an alternative therapy for ADHD, although there are reports in favor of the plant medicine. 

 

• One study of 59 patients revealed that high doses of cannabinol (CBN) was associated with lower self-reported ADHD symptoms as well as an ADHD medication reduction.
• Another larger study of 1,700 students found that cannabis had beneficial effects on ADHD symptoms (e.g., hyperactivity, impulsivity), and improved medication side effects (e.g., irritability, anxiety)
• A 2019 study comparing THC:CBD to a placebo found that there were no significant effects on ADHD symptoms
• A 2020 study of 112 adult ADHD patients reported those who took higher doses of cannabinoid therapies, like CBD, took fewer traditional medications for ADHD
• Three adult patients reported substantial benefits to treating ADHD with cannabis. Quality of life improved, attentiveness scores rose up to 30%, depression improved by up to 81%, and they were able to obtain or excel at a new job with more responsibility. 

 

Why Do People Seek Alternative Therapies for ADHD?

 

Traditional treatments for ADHD can include stimulants such as Adderall and Ritalin, which can produce unwanted side effects. Common side effects include trouble sleeping, loss of appetite, and increased heart rates. In fact, 21% of parents surveyed reported discontinuing the use of ADHD medication for their children due to psychological side effects. Using these prescription stimulants can also lead to substance abuse or dependence. 

 

In addition to prescription medication, doctors often recommend behavioral therapy, either as its own treatment or in conjunction with medication. Behavioral therapy may be limited in desired results, as it offers no solution to symptoms, but rather a set of skills to manage ADHD more easily. 

 

Cannabis Compounds and Terpenes

 

The levels of THC and CBD in varying strains of cannabis plants have differing effects on the brain and body. Ongoing research suggests that CBD may alleviate anxiety, promote better sleep, and improve overall quality of life. Most research in favor of treating ADHD symptoms with cannabis emphasizes the benefits of CBD rich products. This means high CBD low THC ratio options and whole-plant cannabis (containing a range of cannabinoids and terpenes) may provide relief.

 

Currently, a clinical trial on how CBD-rich oil given to adults orally will affect the symptoms of ADHD disorder is underway. The objectives of the study are listed as follows: 

• to characterize the effects of treatment with cannabis oil on symptoms of ADHD
• to compare safety and efficacy of cannabis oil products with different CBD, Cannabidivarin (CBDV), cannabigerol (CBG) and THC ratio;
• to measure endocannabinoids, THC and CBD and metabolites levels in the blood of the participants

 

Research trials like these provide the necessary opportunity to pair hard data with what appears to be promising possibilities for treating ADHD symptoms. In the meantime, we recommend speaking with a medical professional before starting new treatment options such as described above. If you would like to discuss more about the potential benefits of cannabinoid therapy, please reach out to our care team!

 

The cannabis industry is a growing industry and the fastest growing in the United States. Cannabis sales are expected to reach $99 billion in 2022 and projected to reach upwards of $155 billion in 2026. As more and more states pass legislation to legalize cannabis, there is an abundance of cannabis products on the market. The scale of cannabis grows requires more resources, bringing up environmental and societal impacts to be considered in the process.

 

The Environmental Impact of the Cannabis Industry

 

To put into perspective the impacts the cannabis industry can have on the environment, the city of Denver reported in 2018 that nearly 4% of the city’s total electricity usage was a result of cannabis production. A study published in Nature Sustainability estimated that 1.3% of Colorado’s total greenhouse gas emissions were generated by indoor cannabis growing operations. Presently, Denver is seeing a 45% increase in energy electricity demand specifically related to cannabis cultivation.

 

To compare this to other popular industries, cannabis has the highest footprint per unit as opposed to one serving of beer, wine, or cigarettes. The Journal of Cannabis Research reported that cannabis plants use around twice as much water as maize, soybeans, wheat and wine grapes. 

 

“Indoor cannabis cultivation requires a jaw-dropping amount of energy. It’s an antiquated remnant from prohibition that is neither financially nor environmentally sustainable.” – Amy Zents, Director of Cultivation for Progressive Plant Research

 

Currently, the biggest challenges the cannabis industry faces are the energy efficiency, waste management, and water usage required to grow plants. It is projected that by 2025, the cannabis industry will see an 86% rise in water use. The cultivation output is attempting to keep up with the growing demand for cannabis, as it is used both medicinally and recreationally, while simultaneously needing to minimize the impact of resources used. With the cannabis industry still being considered in its infancy, this is an important time for pacemakers to begin to educate and ingrain best practices in their cannabis operations. 

 

Creating a Sustainable Future for Cannabis

 

Through the use of data and science backed technology, the cannabis industry has a hope for a sustainable future. Sustainability will need to be a priority in every part of the industry, from production to packaging to the supply chain. Understanding the amount of resources used to make a cannabis product will vary from business to business, and so it falls in the hands of the establishments to measure and report on their metrics. 

 

Unfortunately, with many small businesses in their early stages, their priorities are often focused on getting the operation up and running, as opposed to understanding the challenges of environmental impact or the opportunities available in sustainable grows. When comparing indoor cultivation to greenhouse growing sites, there are both economic and environmental benefits to the latter. The numbers don’t lie, and greenhouses or hybrid growing sites can require 134 kilowatt hours per square foot, versus 262 for indoor cultivation. 

 

Along with education and acquiring production data metrics, there are a number of ways to achieve a more sustainable cannabis industry. 

 

To start, cultivators should focus on optimizing their energy use. This can be done by upgrading equipment, something that ends up being cost efficient over time, or analyzing performance numbers to see where there is room for improvement in an operation. Identifying trends in business metrics allows for opportunities to improve on energy efficiency. 

 

Understanding and utilizing the technological innovations available is another circumstance for sustainable improvements. Companies often market products that can lower costs and enhance production, for example LED lighting systems with sensors and in depth control options to better regulate grows or switching to solar panels on-site. Technology like this is becoming more and more available, and cultivators are waking up to the realization that these assets can help them not only yield more product but also reduce their energy costs.

 

“Through the use of energy-efficient equipment, integrated controls, and system automation, along with strategic energy management and data analysis, we have reduced our total energy use by over 50%.” – Shawn Cogan, Facilities Director for Progressive Plant Research

 

Energy and water usage aren’t the only sustainability issues cannabis and hemp farmers need to consider. Waste management also poses a huge environmental threat. Chemical waste and pesticides used on crops end up seeping into waterways, causing serious harm. Leveraging an understanding of the plant’s biology data during plant selection can improve agronomic traits, including lower risk of pests, thus resulting in less pesticides needed. Another best practice is to really research the nutrients used for cannabis cultivation. Product knowledge is an important step in ensuring the safest and most sustainable options are used in the production process. 

 

In order to see a truly sustainable future in cannabis, it will require an industry wide effort. Widespread shared ideology on the importance of these practices (energy efficiency, waste reduction, utilizing technologies, etc.) and an implementation of said solutions is the key to success.

 

How Consumers Can Help

 

As a consumer, you can speak with your dollar by shopping from brand’s that prioritize environmental concerns in their cannabis operation. Many businesses market themselves as sustainable and organic, and in some occasions may be greenwashing, so doing your due diligence to confirm these statements are true can help ensure you are purchasing from a brand you can trust. 

 

At Realm of Caring we have a list of Supported Brands on our website. These products have passed our strict quality control guidelines and it is with confidence that we recommend them to you.

Chronic Fatigue Syndrome (CFS) or Myalgic encephalomyelitis (ME) is a debilitating, long-term illness causing severe fatigue and sleep problems. While it is most commonly found in individuals between ages 40 and 60 years old, anyone can be affected by CFS. It is estimated that around 90 percent of people with CFS have not been diagnosed. While there is no cure, symptoms may be treated or managed.

 

Symptoms of CFS include:

 

Post-exertional Malaise (PEM)

Sleep disorders

Pain

Depression, stress, and/or anxiety

Memory and concentration difficulties

 

There is a fair amount of research on how cannabinoid therapy may alleviate these symptoms and more, including results from data collected in Realm of Caring’s Observational Research Registry (ORR). Our research has shown that Cannabis Users reported lower baseline depression, significantly better past-month sleep quality, a higher overall quality of life, and lower past-month average pain compared to Controls. Here we will take a closer look at the aforementioned symptoms and how cannabinoid therapy may benefit. 

 

Post-exertional Malaise (PEM)

 

It is recommended by the medical community to find individual limits for mental and physical activity, if you suffer from CFS. The worsening of CFS symptoms may lead to what is called Post-exertional Malaise (PEM), where physical, mental, or emotional exertion could exaggerate symptoms and cause them to last for days or even weeks. One way to find individual limits that is recommended, is by journaling. This is also a welcome practice with cannabinoid therapy; as it is not a one size fits all approach. If you choose to take this journey it is recommended that you journal symptoms, products you are using, how much you are taking, and how you are feeling overall. Our care specialists are here to walk you through this process as well. 

 

Sleep disorders

 

Common sleep complaints from sufferers of CFS include difficulty falling or staying asleep, extreme sleepiness, vivid dreaming, restless leg syndrome, and muscle spasms. Certain cannabinoids have shown through studies the ability to benefit our sleep-wake cycles, decrease nightmares, lessen the conditions that interfere with our sleep, and assist in actually falling asleep. 

 

Among the several researched properties, cannabidiol (CBD) may benefit as an anxiolytic, anti-inflammatory, and analgesic. The anxiolytic properties of CBD may help to improve sleep by mitigating anxiety or stress-induced insomnia as well as limiting muscle tension anxiety that can lead to spasms or restless legs. Stress induces a sleep-related feature known as rapid eye movement (or REM) sleep rebound. This is an increase in REM sleep during the nightly sleep cycles. People experiencing REM sleep rebound may spend more time in REM than they would during a night of normal, healthy sleep. Studies show that therapeutic levels of CBD administration may increase total sleep time and decrease frequency of arousals at night – leading to an increase in total percentage of sleep overtime. 

 

Pain

 

People living with CFS, often mention the joints and muscles being areas of the highest pain. They may also suffer from pressure headaches. Cannabis use for pain can be traced back thousands of years. In 2900 B.C. ancient Chinese texts show written records of cannabis as a medicine. More recently, data from clinical trials on synthetic and plant-derived cannabis-based medicines have suggested that they are a promising approach for the management of chronic pain of various origins. Pain is produced by pro-inflammatory agents that also lead to an increased sensitivity to feeling pain and an extreme response to pain, or hyperalgesia. The anti-inflammatory properties of cannabinoids are becoming more well known through increased research to combat pain induced by inflammation.

 

Cannabinoids that may perform best as potent anti-inflammatory agents are CBD, Tetrahydrocannabonolic acid (THCa), Cannabidiolic acid (CBDa), and THCV (Tetrahydrocannabivarin). Therapy to include these cannabinoids may help to ease the inflammation on the surrounding tissue of the joints, as well as muscles to decrease tension, soreness, and pain. 

 

Depression, stress, and/or anxiety

 

CBD works as a modulator to our physiological processes. This includes how effectively our body may facilitate the serotonin it creates, allowing more of that “happy chemical” to be made available for our brains and, therefore, regulating our moods. Just as it helps to move serotonin along, CBD may also help with the functioning of GABA, the neurotransmitter that regulates our nerve signals; therefore aiding in the reduction of our anxiety, panic, and stress response.

 

Data show that repeated administration of CBD may produce effects consistent with results from studies that test traditional anti-anxiety and antidepressant medications. These are known as clinically relevant findings because CBD is known to benefit while exhibiting few side effects, supporting the initiation of clinical trials testing the efficacy of CBD-based compounds for the treatment of mood disorders. 

 

Memory and concentration difficulties

 

Prolonged CBD therapy has shown positive improvements in psychological symptoms and cognition. Currently, using cannabinoids to benefit neurological issues and serve as a neuroprotectant is being studied. The antioxidant properties of cannabinoids, such as CBD, may have the ability to provide neuroprotection. As well, research is showing that elevation of cannabinoid receptor activity could potentially slow down the progression of brain aging and alleviate symptoms associated with neurodegenerative disorders, therefore cannabinoids with the ability to activate receptors may provide these additional benefits. 

 

While struggling with a condition as debilitating as CFS, it is important to talk with a medical professional about your options. Complementary therapies and a strong focus on wellness may improve cannabinoid therapy results as well as decrease symptoms further. If you would like to discuss more about the potential benefits of cannabinoid therapy, please reach out to our care team!

 

 

Disclaimer

 

The Realm of Caring Foundation specifically invokes the first amendment rights of freedom of speech and of the press without prejudice. These statements have not been evaluated by the food and drug administration. The products discussed are not intended to diagnose, cure, prevent or treat any disease. Realm of Caring always recommends when and wherever possible that licensed local healthcare professionals be consulted.

 

The Realm of Caring Foundation is an independent nonprofit with its own governing board. We do not produce or sell cannabinoid products, nor do we receive funds from the sale of other company’s products.

Have you ever been so desperate for your medicine or therapy to work that you place all your eggs in one basket? We all have! You might be thinking, “I hope this pill cures my insomnia,” or “this oil better take away my chronic pain!” Often times we put so much hope, confidence and faith in a single mechanism, when we should really be including multiple tools to “fix” our system. That is why we created this comprehensive infographic to help our clients understand our Wellness Tool Kit; it is a comprehensive set of tools that are vital to maintaining and managing your health. Even though Realm of Caring’s primary expertise is cannabinoid therapy, we want to acknowledge the multiple assets that can support a sustainable and healthy lifestyle. The tool kit is an important reminder that cannabinoid therapy alone is not a silver bullet, meaning cannabis on its own may not be the magical solution to your problem. Healthy diet, sleep, exercise, and water are just a few of the other tools in your kit that can help you achieve your goals. 

 

Why is cannabinoid therapy a powerful tool in your tool kit? 

 

This plant packs one powerful punch! With more than 500 different components that carry potential therapeutic qualities, this plant can affect several targeted areas in the body. A recent review titled, Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug, points out that the plant can treat multiple conditions throughout the body. With so many phytocannabinoids, terpenes, and flavonoids working together with your body’s endocannabinoid system, cannabis is a multi-faceted fixer. The plant helps the endocannabinoid system modulate and regulate many processes in the body like pain, digestion, coordination and neural development. 

 

How will you measure the success of your tools? 

 

There are several health apps and online tools that can help you track everything you are doing in order to achieve your goals. Even a notebook will suffice; Dr. Gail Matthews led a study on goal-setting that found participants were 42% more likely to achieve their goals if they wrote them down daily. Incorporating your tools into your goal setting is a great way to ensure that you are using multiple strategies and not just relying on one method to fix your problem. Another way to track your progress is participating in the Realm of Caring’s Observational Research Registry (ORR). This online survey examines the health effects of medicinal cannabis use and is open to anyone in the world with internet access. If you choose to participate, you will be asked questions about your use of cannabis/hemp products, other medications, and general health. 

 

How can Realm of Caring help you? 

 

Our Care Team is here to help you navigate cannabinoid therapy as one tool in your tool kit. Based on data from our IRB approved observational research registry, we can help you dial in this therapeutic approach to wellness. Call us at 719-347-5400 option 1, email us at info@realmofcaring.org, or visit our website and sign up for a free client account at www.realmofcaring.org.

 

 

Disclaimer

 

The Realm of Caring Foundation specifically invokes the first amendment rights of freedom of speech and of the press without prejudice. These statements have not been evaluated by the food and drug administration. The products discussed are not intended to diagnose, cure, prevent or treat any disease. Realm of Caring always recommends when and wherever possible that licensed local healthcare professionals be consulted.

 

The Realm of Caring Foundation is an independent nonprofit with its own governing board. We do not produce or sell cannabinoid products, nor do we receive funds from the sale of other company’s products.

 

Tobacco use is responsible for more than 480,000 deaths each year in the U.S., according to the CDC, which estimates that it accounts for nearly one of every five deaths annually.

 

Tobacco use is responsible for more than 480,000 deaths each year in the U.S., according to the CDC, which estimates that it accounts for nearly one of every five deaths annually. It is the leading cause of preventable death in this country; there are approximately 1,300 deaths from smoking each day. Tobacco use is a major risk factor for heart disease, cancer and lung disease—and these diseases kill more people than any other health problem. The good news is that by quitting smoking and tobacco use, you can reduce your risk of developing many serious health problems. Even better news? Cannabinoids may help curb tobacco addiction and even assist you in this process.

 

New research shows that compounds found naturally in cannabis plants reverse attentional bias to cigarette cues in a human experimental model of tobacco withdrawal.

 

New research shows that compounds found naturally in cannabis plants reverse attentional bias to cigarette cues in a human experimental model of tobacco withdrawal. The study, published in the National Library of Medicine, shows that treatment with cannabidiol (CBD), a non-psychoactive cannabinoid found naturally in cannabis, may be a promising novel smoking cessation treatment due to its anxiolytic properties, minimal side effects and research showing that it may modify drug cue salience.

 

Researchers used an experimental medicine approach with thirty non-treatment seeking dependent cigarette smokers, by administering 800 mg oral CBD or matched placebo (PBO) in a counterbalanced order. Withdrawal, craving, side effects, heart rate and blood pressure were repeatedly reviewed. The results showed that a single 800‐mg oral dose of cannabidiol reduced the salience and pleasantness of cigarette cues, compared with placebo, after overnight cigarette abstinence in dependent smokers. Cannabidiol did not influence tobacco craving or withdrawal or any subjectively rated side effects. These findings suggest that cannabidiol may hold promise for aiding in nicotine withdrawal, and may also be effective in improving other addictive behaviors.

 

Further promising results from preclinical studies suggest that manipulation of the endocannabinoid system could be a potential therapeutic strategy for treating nicotine addiction.

 

Further promising results from preclinical studies suggest that manipulation of the endocannabinoid system could be a potential therapeutic strategy for treating nicotine addiction. The possible involvement of the endocannabinoid system in the rewarding effects of nicotine was evaluated by using the conditioned place preference (CPP) in mice.

 

Researchers set out to examine the role of cannabinoid receptors in the brain’s reward circuitry by evaluating the CPP in mice, and were surprised to learn how critical they are for mediating nicotine reinforcements in the rodents. The scientists found that the brain’s response to nicotine triggers the activity of cannabinoid receptors and increased levels of an important enzyme called cPLA2, which is involved in activating these receptors. They then demonstrated that inhibiting cPLA2 activity dramatically reduced nicotine reinforcement by preventing the activation of cannabinoid receptors. Such findings suggest that promoting cannabinoid receptor signaling in the brain could be useful in treating nicotine addiction and other substance abuse disorders, although it is too soon to recommend cannabis as a solution to curbing tobacco addiction.

 

When quitting smoking, CBD may be a promising therapeutic tool to help ease withdrawal symptoms.

 

CBD seems to be a promising therapeutic tool due to its anti-inflammatory, anxiolytic, neuroprotective, and non-psychoactive effects. In humans, treatment with CBD has been reported to reduce cigarette consumption and pleasantness of cigarette cues after overnight abstinence.

 

Kicking a nicotine addiction is hard, and often the hardest part for addicts is getting through the uncomfortable withdrawal symptoms that many fall victim to, thus keeping them in a cycle of dependency on cigarettes and nicotine-containing products. Some symptoms of nicotine withdrawals that CBD can aid in relief of may include anxiety, irregular sleep patterns, headaches, nausea, and irritability.

 

For those looking for a natural ally in curbing tobacco addiction, CBD could be an effective aid. Choosing quality products from reliable retailers is an important part of this process. We recommend checking out our list of supported brands.

 

At Realm of Caring, we believe in taking an individual approach to cannabinoid therapy to find a product and dose that works for each of us! If you would like to reach out to our Care Team (719-347-5400 option 1), they would be happy to help you individualize your therapy and find a product that is right for you.

Delta-8 tetrahydrocannabinol (delta-8 THC) has become a growing topic of discussion due to its legal controversy and recently issued warning letters by the FDA. The FDA’s growing concerns stem from companies reported to have illegal marketing and drug misbranding. Delta-8 is currently legal in 32 states, however this could change rapidly as states are beginning to regulate or create legislation to prohibit products containing the compound completely. Before we dive into the legal gray area, let’s review what exactly delta-8 THC is.

 

What is delta-8 THC?

 

Delta-8 THC is one of the cannabinoids produced naturally by the cannabis plant, but is not found in significant amounts of the cannabis plant. Concentrated amounts of delta-8 THC are typically manufactured from hemp-derived cannabidiol (CBD). However less psychoactive than delta-9 THC, delta-8 THC still has similar psychoactive and intoxicating effects to delta-9 THC, the cannabinoid most popular in the cannabis plant for getting people “high”.

 

The two compounds are almost identical in structure except for the location of a double bond. The double bond is found on the 8th carbon in delta-8’s structure and the 9th carbon in delta-9. This difference of the double bond location makes delta-8 less potent, meaning that individuals may be able to tolerate more per administration. The effects of delta-8 have been reported by users as mild euphoria, happiness, uplifting feelings, and relief of pain.

 

Is Delta-8 THC a synthetic cannabinoid?

 

Because delta-8 THC is not found in significant amounts in cannabis some assume that it is a synthetic cannabinoid, or man made, but it is a natural compound. Delta-8 products do, however, require manual intervention for there to be a consumable amount available. While it is not a synthetic cannabinoid, it is synthetically derived. 

 

Delta-8 THC Federal Legal Standing

 

Delta-8’s current legal standing is controversial on the federal level. Interpreting it as legal is due to a loophole through The Farm Bill. In 2018, the Farm Bill removed hemp with very small concentrations of THC from the definition of marijuana in the Controlled Substances Act. Hemp is defined as products derived from the cannabis plant containing less than 0.3% of delta-9 THC. Tetrahydrocannabinol’s are listed by the DEA as a Schedule I drug, “except for tetrahydrocannabinols in hemp“. Because of the federally legal status of hemp, manufacturers have derived delta-8 using a conversion process from CBD. 

 

Delta-8 THC State Legal Standing 

 

Many states have begun to regulate delta-8 THC due to the lack of research on its effects and considering it is synthetically derived. 

 

Delta-8 THC is currently prohibited or illegal in these 13 states: Alaska, Colorado, Delaware, Idaho, Iowa, Montana, Nevada, New York, North Dakota, Rhode Island, Vermont, Utah and Washington. The reasoning for the ban of Delta-8 THC products can be summed up by the Colorado Department of Public Health and Environment as “chemically modifying or converting any naturally occurring cannabinoids from industrial hemp is non-compliant with the statutory definition of ‘industrial hemp product’.”

 

Connecticut and Michigan regulate Delta-8 THC the same way they do recreational cannabis. State authorities in Arizona, California and Mississippi have not released a clear statement on whether delta-8 is legal, partially illegal, or completely illegal. 

 

Finally, Delta-8 THC is currently legal in these 32 states:  Alabama, Arkansas, Florida, Georgia, Hawaii, Illinois, Indiana, Kansas, Kentucky, Maine, Maryland, Massachusetts, Minnesota, Missouri, Nebraska, New Hampshire, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Virginia, West Virginia, Wisconsin, Wyoming, and in Washington D.C.

 

What does this all mean for the future of Delta-8 THC?

 

It should come as no surprise that the legality surrounding this newly popularized cannabinoid is confusing and even contradicting in some states. The legal gray area is something the cannabis industry knows intimately and it is suggested to keep an eye on your state’s legislation because that is likely to change before the federal level. Overall, at the Realm of Caring we always advocate for more research so that we can have a better understanding of all aspects of the cannabis plant. If you support the research & education of cannabis, please consider making a donation here or joining our Observational Research Registry (ORR).

 

 

Disclaimer

The Realm of Caring Foundation specifically invokes the first amendment rights of freedom of speech and of the press without prejudice. These statements have not been evaluated by the food and drug administration. the products discussed are not intended to diagnose, cure, prevent or treat any disease. Realm of Caring always recommends when and wherever possible that licensed local healthcare professionals be consulted.

The Realm of Caring Foundation is an independent nonprofit with its own governing board. We do not produce or sell cannabinoid products, nor do we receive funds from the sale of other company’s products.

 

Update 5/11/22

 

We’re pleased to announce that this new version of the bill, with slight technical amendments, was overwhelmingly passed by the Colorado House and Senate during the final day of the session. Here’s the final bill. In summary, this legislation will:

 

• Create a task force of hemp and marijuana industry representatives and government officials to intentionally study the topic of intoxicating compounds and propose legislative and rule recommendations. The task force will have broad representation from regulators, manufacturers, refiners, retailers, labs, consumer nonprofit organizations, and adult-use patients, and is intended to ensure that all viewpoints are captured and incorporated in whatever recommendations develop.
• Provide immediate authority to the Colorado Department of Public Health & Environment to develop regulations to prohibit the sale of chemically-converted and synthetically-derived intoxicating THC isomers.
• Provide immediate authority—and nearly $600,000 in funding—to the Colorado Attorney General to crack down on deceptive trade practices and other consumer protection issues regarding hemp products.

 

The legislation has been sent to Governor Jared Polis, who is expected to sign it shortly. We are grateful to the Governor, his staff, legislative leaders, and especially YOU, for your swift take action.  They listened to the hemp industry’s concerns and helped transform a flawed bill into one that will address our mutual concerns.

 

 

UPDATE 5/3/22:

 

In policy, if everyone is only a little unhappy, you probably are in a good place. We worked hard with the hemp industry, stakeholders, lobbyists as well as President Fenberg to come to consensus language on SB205 on 5/2/22.

 

You are the HERO: Your rapid take action allowed this committee to see that what they were being told by the Big Marijuana Lobby, (we agree with their 15-page bill that would secretly kill hemp in CO)  was… in fact –  a lie.  The committee, and particularly President Fenberg took control of the circus along with Mark Ferrandino, Executive Director at the Colorado Department of Revenue to get to a place most people could live with and do the three things that we felt were most important:

 

1. Protect access to the products that our families have grown to rely on for the last decade. 
2. Allow the regulatory body to have the clarity to regulate the bad actors masquerading their intoxicating, and chemically synthesized (Delta 8 and Delta 10 THC) products as hemp. 
3. Create a Task Force so that Colorado can develop more regulatory structures around hemp with all the stakeholders at the table. 

 

4/29/22

Do you or a loved one rely on hemp products everyday? This week’s blog is all about the Colorado Bill: SB 22-205 and what you can do to help us take action now! The products you rely on are in jeopardy. With your voice, effort and support, we can let our Colorado representatives know that we will not stand for this.

 

 

What is the name of the bill and where can I read about it online? 

 

SB22-205

 

Intoxicating Hemp And Tetrahydrocannabinol Products: Concerning the regulation of cannabis-related products that may potentially cause a person to become intoxicated when used. SESSION: 2022 Regular Session

 

Read it here: https://leg.colorado.gov/bills/sb22-205

 

 

Who does this affect? 

 

• Hemp companies that operate in Colorado and ship nationwide. 

 

• Consumers who buy these hemp products. 

 

 

What does the bill do? Why is it a problem? 

 

 

• Non-intoxicating hemp extract tinctures would be limited to 20 mg of THC per bottle, with criminal penalties and/or civil rights of action for violations.  This would virtually wipe out full spectrum hemp tincture commerce.

 

• The bill would require Colorado CBD manufacturers to immediately destroy much of their stock of non-intoxicating full-spectrum products that exceed the 20 mg THC package cap (including tinctures, caplets, gummies, etc.), prohibiting them from selling these products to states where they are legal, and potentially imposing criminal and civil penalties on their storage and distribution.

 

• In determining whether future cannabinoid products are intoxicating, the law would not require a scientific analysis and could lead to improperly classifying some novel non-intoxicating compounds as adult-use cannabis. For example, CBN that naturally occurs in hemp products. 

 

• The legislation does not provide a certain path to protect the retail sale of CBN products that are demonstrably non-intoxicating. Protections for non-intoxicating products are limited to CBD, CBG, and CBC (and acids), stifling all innovation.

 

• There would be no grace period whereby retailers could sell non-intoxicating products that are packaged legally as of today but would fall outside the new limits.  There are also no safe harbors for manufacturers handling in-process or bulk ingredients. This would require small businesses to immediately destroy intoxicating products that complied with the rules when they were manufactured or face possible criminal penalties.

 

 

What is happening right now? 

 

Fortunately, we were able to work with the Hemp Industry to get new language in and we need to shout loud and clear to support the Hemp Industry amendment.  

The new amended language would:

 

1. Allow the Colorado Department of Public Health and Environment (CDPHE) in conjunction with the Attorney General’s Office be empowered with the authority to immediately enforce against both retail and online sales of hemp products that contain substantially more than 2.0 mg of delta-9 THC per serving, as well as other products that are likely to cause intoxication or marketed as intoxicating, such as delta-8 and delta- 10 THC.
2. Will also require CDPHE and the Marijuana Enforcement Division (MED) within the Department of Revenue (DOR) to work together on a collaborative, stakeholder-driven rulemaking process that utilizes science-based standards to determine which hemp products should be designated as intoxicating.

 

What is the bottom line?

 

Intoxicating hemp products for retail sale in Colorado are increasingly becoming an issue and the Colorado Hemp Industry as a whole is united behind addressing this problem. However, Senate Bill 205 was hastily drafted with input only from the Marijuana industry and out of state interests who seek to disadvantage hemp manufacturing in the state of Colorado and would cause irreparable economic damage to thousands in our state whether it is from consumers who rely on affordable access to full spectrum hemp products or manufacturers who provide over a thousand jobs in rural communities. This bill is overreaching and will prevent you and I from getting the hemp products you have trusted for the last 10 years.

 

 

 

 

If you would like to talk to a care specialist about this please call 719-347-5400 ext 1 or email info@realmofcaring.org