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The Endocannabinoid System of Animals
Our understanding of the Endocannabinoid System of animals, and its ubiquitous presence in nearly all members of Animalia, has opened the door to novel approaches targeting pain management, cancer therapeutics, modulation of neurologic disorders, stress reduction, anxiety management, and inflammatory diseases. Both endogenous and exogenous endocannabinoid-related molecules are able to function as direct ligands or, […]
Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats
The use of cannabidiol (CBD)-rich hemp-based nutraceuticals is increasing in dogs and cats for disorders related to anxiety, seizures, cancer and pain. To date, there is little information related to appropriate dosing or long-term effects on serum chemistry or complete blood counts (CBC), and little data on the pharmacokinetics of single- or long-term dosing in […]
Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs
Abstract Objectives: The objectives of this study were to determine basic oral pharmacokinetics, and assess safety and analgesic efficacy of a cannabidiol (CBD) based oil in dogs with osteoarthritis (OA). Methods: Single-dose pharmacokinetics was performed using two different doses of CBD enriched (2 and 8 mg/kg) oil. Thereafter, a randomized placebo-controlled, veterinarian, and owner blinded, […]
Use of Cannabidiol for Canine Medical Conditions
Due to the myriad of laws concerning cannabis, there is little empirical research regarding the veterinary use of cannabidiol (CBD). This study used the Veterinary Information Network (VIN) to gauge US veterinarians’ knowledge level, views and experiences related to the use of cannabinoids in the medical treatment of dogs. Participants (n = 2130) completed an […]
A selective review of medical cannabis in cancer pain management
Cancer is one of the most common reported conditions for using medical cannabis. This review can be useful to practitioners and policy makers when making decisions on use for cancer patients and cannabis in the future. Insufficient management of cancer-associated chronic and neuropathic pain adversely affects patient quality of life. Patients who do not respond […]
Medical Cannabis: Effects on Opioid and Benzodiazepine Requirements for Pain Control
The United States is currently undergoing a tragic opioid epidemic. We have a duty to try to curb this disaster. This study shows that by taking cannabis as an adjunct treatment, patients may be able to lower the amount of opioids needed to find pain relief. Abstract Background: There is currently little evidence regarding the […]