Category: Blog

If you’ve browsed a CBD store or hemp dispensary lately, you may have come across terms like “Delta-8 THC,” “Delta-9 THC,” and “hemp-derived THC.” They may sound similar, but the differences between them can have a big impact on how they affect your body – and your legal standing depending on where you live.

 

At Realm of Caring, we are here to help you make informed, empowered decisions. Whether you are exploring plant-based therapies for the first time or are a seasoned cannabis consumer, understanding how different forms of THC behave in the body is essential.

 

What is THC, Anyway?

 

THC, short for tetrahydrocannabinol, is the primary intoxicating compound found in cannabis. It binds to CB1 receptors in the brain and nervous system, which can influence mood, memory, pain perception, appetite, and more.

 

When most people refer to THC, they’re talking about Delta-9 THC, the compound responsible for the classic “high” associated with cannabis. But due to evolving laws and consumer demand, other forms of THC have emerged in the market,  including Delta-8 THC and hemp-derived Delta-9 THC.

 

Delta-9 THC: The Classic Compound

 

Delta-9 THC is the most researched and abundant form of THC found naturally in the cannabis plant. It’s well known for its intoxicating effects at moderate to high doses, and it has also been studied for potential medicinal and therapeutic uses including:

 

• Reducing nausea and vomiting (especially during chemotherapy)
• Stimulating appetite
• Supporting pain relief
• Easing muscle spasticity (especially in conditions like MS)

 

Because Delta-9 THC is federally classified as a Schedule I controlled substance, it is still highly regulated. However, hemp-derived Delta-9 THC (less than 0.3% by dry weight, per the 2018 Farm Bill) is allowed under federal law, a nuance that some companies use to sell THC-containing edibles, vapes, and tinctures nationwide.

 

Consumer Tip: While hemp-derived Delta-9 is legal in many states, it still produces the same psychoactive effects. Always start with a low dose and understand how your body reacts.

 

Delta-8 THC: A Close Cousin, But Not the Same

 

Delta-8 THC is a cannabinoid that occurs in very small amounts naturally in hemp and cannabis. To produce Delta-8 products at scale, manufacturers typically convert CBD into Delta-8 through a chemical process called isomerization, which alters the molecular structure.

 

Delta-8 and Delta-9 THC are nearly identical, sharing the same molecular formula (C₂₁H₃₀O₂), (which also happens to be the same molecular formula as cannabinoids cannabichromene (CBC) and cannabidiol (CBD), and the hormone progesterone) and both bind to CB1 receptors in the brain. But Delta-8 is generally considered potentially less potent and less intoxicating, which has made it popular among people seeking relief without a strong high.

 

Some promising studies, including research in pediatric cancer patients, show Delta-8 may help reduce nausea with fewer side effects than Delta-9 THC. In mouse models, it has also shown the potential to increase appetite and cognitive performance without as much psychoactivity.

 

However, most Delta-8 THC on the market is synthetically derived and unregulated. This means:

 

• There is limited oversight on how it’s produced
• Lab testing is inconsistent or absent
• Products may contain contaminants or significantly more THC than advertised

 

Many states have taken action to ban or restrict Delta-8 sales due to concerns about consumer safety, especially when products skirt regulations intended for marijuana-derived THC.

 

Consumer Tip: Be cautious with Delta-8. Look for third-party lab tests and avoid products that don’t disclose how the cannabinoid was derived or what’s in it.

 

Hemp-Derived THC: Legal Loopholes and Consumer Confusion

 

The term “hemp-derived THC” typically refers to cannabinoids like Delta-8 or Delta-9 that are sourced from hemp (cannabis plants with less than 0.3% Delta-9 THC by dry weight). Because of this federal definition, manufacturers are able to infuse hemp-derived cannabinoids into edibles and oils, sometimes containing enough THC to produce intoxicating effects, even if technically compliant with the letter of the law.

 

While this may seem like a win for accessibility, it creates a confusing consumer landscape. Products may appear to be CBD-only or “non-psychoactive” based on hemp labeling, but in reality they can:

 

• Cause a THC high
• Show up on a drug test
• Contain synthetic or unregulated compounds

 

As a result, consumers seeking non-intoxicating relief may unknowingly purchase products that affect their cognition, coordination, or overall health.

 

Consumer Tip: Read labels and seek transparency with a company prior to purchasing. 

 

Awareness is Everything

 

All forms of THC – whether Delta-9, Delta-8, or hemp-derived – have psychoactive potential at certain doses. The key difference lies in how they’re made, how much we know about their safety, and how they’re regulated.

 

At Realm of Caring, we advocate for transparency, research, and consumer safety. Here’s what we recommend:

 

• Start low and go slow, especially with new or unfamiliar products
• Ask for Certificates of Analysis (COAs) from third-party labs
• Choose products from trusted sources that explain their extraction process
• Stay up-to-date on your state laws

 

And most importantly, don’t be afraid to ask questions. Our care team is here to help you navigate the world of cannabis with confidence.

 

Each July, National Hemp Month offers us a moment to reflect on the incredible potential of the hemp plant—not just as a source of therapeutic cannabinoids, but also as a powerhouse of nutritional wellness. While much attention is rightly given to cannabinoids like CBD and THC, hemp seeds deserve their own spotlight. Rich in essential fatty acids, hemp seeds provide a near-perfect balance of Omega-6 to Omega-3—an attribute that sets them apart from many other plant-based foods.

 

 

Why Omega Fatty Acids Matter

Omega-6 and Omega-3 are polyunsaturated fatty acids (PUFAs), meaning they are crucial for human health but must be obtained through diet. These fats play essential roles in:

• Supporting brain function and development
• Regulating metabolism and hormone production
• Reducing inflammation
• Promoting cardiovascular health

While both are essential, modern diets often over-index on Omega-6 (commonly found in processed seed oils) and under-consume Omega-3s, leading to an imbalanced ratio that may increase the risk of chronic disease [1].

 

 

The Ideal Ratio—and How Hemp Delivers

Health experts recommend an Omega-6 to Omega-3 ratio close to 4:1 or even 2:1, yet the typical Western diet can skew as high as 20:1 [2]. This imbalance has been linked to increased inflammation, which may play a role in conditions such as arthritis, cardiovascular disease, and metabolic syndrome [3].

Enter hemp seeds: uniquely balanced with a 3:1 ratio of Omega-6 to Omega-3 fatty acids—just what our bodies crave [4]. This makes hemp one of the most effective plant-based sources for restoring equilibrium in our fat intake.

 

 

Gamma-Linolenic Acid (GLA): A Unique Benefit

Hemp seeds also contain gamma-linolenic acid (GLA), a less commonly found Omega-6 fatty acid with notable anti-inflammatory properties. GLA has been studied for its potential to support:

• Hormonal health, especially in those with PMS or menopausal symptoms [5]
• Skin conditions like eczema and dermatitis [6]
• Immune system balance

This makes hemp seeds particularly supportive for individuals looking to integrate whole-body wellness through nutrition.

 

 

Whole Food, Whole Body Benefits

Incorporating hemp seeds into your daily routine is easy and beneficial. A couple of tablespoons offer:

• 10 grams of protein
• 12 grams of Omegas
• Vital minerals such as magnesium, iron, and zinc
• A complete amino acid profile

This nutrient density supports overall wellness—nourishing the body, brain, and beyond.

 

 

Hemp and the Bigger Picture

At Realm of Caring, we believe in exploring the full spectrum of hemp’s therapeutic potential. Whether it’s participating in groundbreaking cannabinoid research or educating on the plant’s nutritional gifts, our mission is rooted in holistic health and evidence-based care.

As we celebrate National Hemp Month, let’s honor the often-overlooked power of hemp seeds. Adding them to your smoothie, oatmeal, salad, or favorite baked goods isn’t just a culinary choice—it’s a wellness strategy grounded in science.

 

References

[1] Simopoulos, A. P. (2002). The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & Pharmacotherapy, 56(8), 365–379.
[2] Lands, W. E. M. (2012). Historical perspectives on the impact of n-3 and n-6 nutrients on health. Progress in Lipid Research, 50(5), 345–352.
[3] Patterson, E. et al. (2012). Health implications of high dietary omega-6 polyunsaturated fatty acids. Journal of Nutrition and Metabolism, 2012, 539426.
[4] House, J. D. et al. (2010). Nutritional composition of hemp seed and products. Journal of Agricultural and Food Chemistry, 58(22), 11801–11807.
[5] Horrobin, D. F. (1993). Gamma linolenic acid in the treatment of PMS. American Journal of Clinical Nutrition, 57(5 Suppl), 847S–852S.
[6] Morse, N. L. et al. (2010). Benefits of GLA in skin conditions. Journal of Dermatological Treatment, 21(3), 129–134.

 

At Realm of Caring, we believe in meeting people where they are, whether they’re exploring cannabis for the first time or looking for new options when other methods fall short. Suppositories are one such option, and while they may not be mainstream yet, they’re offering meaningful relief to people of all genders.

 

 

CBD and Cannabis Suppositories: A Groundbreaking Option for Targeted Relief

 

When we talk about cannabis wellness, most people think of tinctures, gummies, capsules, or inhalation. But there’s a lesser-known method that’s gaining attention for its effectiveness, especially when targeted relief is needed: suppositories.

 

 

What Are Suppositories?

 

Cannabis suppositories are small, moldable forms, typically made with cocoa butter, that are inserted vaginally or rectally. They contain cannabinoids like CBD, THC, or a combination, and are designed to melt and absorb into nearby tissues, delivering effects locally and systemically.

 

Unlike oral methods, suppositories bypass the digestive system and liver, allowing for higher absorption and fewer psychoactive effects, even when THC is present. This makes them an appealing option for those who want the benefits of cannabis without the “high.”

 

 

Why This Method Matters

 

Cannabinoids delivered via suppositories may provide faster relief and better bioavailability than oral consumption. The mucosal tissues in the rectum and vagina are rich in blood vessels, which means cannabinoids can enter the bloodstream directly.

 

This method can be especially beneficial for those with:

• GI sensitivities
• Difficulty swallowing or digesting oral products
• A need for local, pelvic-area support

 

 

Benefits for Women

 

Women are finding cannabis suppositories helpful for a wide range of concerns:

• Menstrual cramps and bloating
• Endometriosis, a condition that often goes underdiagnosed and undertreated
• Sexual health, helping with lubrication, tension, and relaxation
• Menopause symptoms, including dryness, anxiety, and insomnia

 

By applying cannabinoids directly where inflammation and tension occur, some women report profound and fast-acting relief, often within 15 to 30 minutes.

 

 

Benefits for Men

 

While less frequently discussed, men are also benefiting from rectal cannabis suppositories. This method may help:

• Prostate and pelvic inflammation
• Rectal discomfort (including from hemorrhoids or IBD)
• Chronic pain and insomnia

 

For men seeking non-oral options or those navigating conditions like prostate cancer or GI disorders, suppositories offer a discreet, non-invasive, and potentially powerful therapeutic route.

 

 

Considerations Before You Try

 

Suppositories may be unfamiliar to many, so education is key:

• Start low and go slow – especially if THC is included
• Use clean hands or gloves for insertion and lie down for optimal absorption
• Store products in a cool, dark place to maintain integrity
• Speak to your healthcare provider if you’re undergoing other treatments or using prescription medications

 

As always, Realm of Caring is here to guide you with science-backed resources and personalized support.

 

Looking Ahead: The Need for Research

 

While anecdotal evidence is promising, there’s still much to learn. Realm of Caring is committed to supporting the research that will better inform use, access, and policy around cannabis therapies, including suppositories. We encourage curious consumers and medical professionals alike to stay engaged as the science evolves.

 

Join a Realm of Caring study today!

 

Final Thoughts

 

Suppositories may not be the first thing you think of when you consider cannabis therapy, but for many, they’ve become a game-changer.

 

If you’re looking for localized relief without systemic side effects, or you simply want to expand your wellness toolkit, suppositories might be worth exploring.

 

We’re here to answer your questions, connect you with the right resources, and make sure that everyone – regardless of gender, condition, or background – has access to safe, informed, and empowering plant-based care.

 

June is Men’s Health Month, a time to spotlight the unique health challenges men face and empower them with tools that support long-term wellbeing. In recent years, cannabis has emerged as a promising ally in men’s health – supporting everything from stress and sleep to inflammation, sexual health, and emotional balance. While stigma still lingers, education and research are helping men reframe cannabis use as a legitimate part of a proactive health and wellness routine.

 

At Realm of Caring, we’ve spoken with countless male clients who’ve turned to cannabinoids, like CBD, THC, CBG, and more, not to escape, but to engage: with their families, their physical health, their mental clarity, and their personal goals.

 

Stress and Mental Health: The Silent Struggle

 

Many men are conditioned to “tough it out,” avoiding mental health support or downplaying stress and anxiety. But this strategy can backfire, leading to chronic stress, high blood pressure, poor sleep, and even depression. That’s where cannabis-based therapies may offer a gentler path forward.

 

Cannabinoids interact with the body’s endocannabinoid system (ECS), which helps regulate mood, sleep, pain, and immune function. For some men, adding CBD or a balanced CBD:THC product to their wellness regimen may help:

 

• Reduce anxious thoughts 
• Improve emotional regulation 
• Support deeper, more restorative sleep 
• Increase presence and resilience in daily life 

 

One study showed that low-dose THC may reduce anxiety, while CBD appears to have anxiolytic (anti-anxiety) properties without intoxication. But the key is intentional use, not excess. Realm of Caring’s free guided support can help individuals and caregivers personalize their cannabinoid use to avoid common pitfalls and maximize benefit.

 

Read more: Managing Stress with Cannabis – Men’s Health Awareness

 

Physical Wellness: From Inflammation to Hormonal Health

 

As men age, inflammation, pain, and hormone fluctuations (especially testosterone) can impact vitality. Cannabis may offer support in these areas too.

 

• Chronic Pain & Inflammation: Cannabinoids like CBD and CBG show anti-inflammatory properties and may support recovery from workouts, injuries, or chronic pain conditions. 
• Sleep Quality: THC, when used responsibly in low doses, may help men fall asleep faster and sleep longer, while CBD may help with staying asleep and waking feeling refreshed. 
• Sexual Health: While research is still growing, some men report increased libido and improved sexual function, likely due to cannabis’s ability to lower anxiety, boost blood flow, and enhance sensation. 
• Metabolic Health: Emerging evidence links cannabis use with a lower prevalence of obesity and improved insulin sensitivity, but this depends on dose, product type, and lifestyle factors. 

Read more: Cannabis Use and Men’s Health

 

Breaking Stigma, Building Confidence

 

Cannabis is not a cure-all, but for many men, it’s a powerful part of a holistic health plan that includes regular check-ups, movement, healthy food, and open conversations about stress, emotions, and goals.

 

Through our research collaborations and observational studies with institutions like Johns Hopkins University, Realm of Caring continues to document how cannabis supports real people across a variety of health conditions. Our community-based model empowers men to track outcomes, improve their quality of life, and make informed decisions, not guesses.

 

How Realm of Caring Can Help

 

• Free one-on-one support: Talk to a care specialist who can help you or a loved one start a cannabinoid routine based on science, not hype. 
• Cannabis Research Library: Explore peer-reviewed findings on cannabis and men’s health. 
• Education & Advocacy: Learn how to advocate for your health and access safe, reliable products. 

 

We’re here to help you make confident decisions in your wellness journey. Because self-care is not weakness; it’s strength.

This past week, Realm of Caring’s Executive Director, Sasha Kalcheff-Korn, moderated one of the most future-focused conversations at the Benzinga Cannabis Capital Conference. The panel, “Pharma-Grade Cannabis: A Long-Term Play for Investors & Operators Alike?”, brought together a powerhouse lineup of experts pioneering the next era of cannabis as medicine:

 

• Steve Bastasini, Co-Founder & CEO of Kanavos, Inc.
• Jim Sanfilippo, Co-Founder & CEO of VIST Labs
• Duncan Mackie, PhD, Director of Pharmacology & Experimental Therapeutics at Bud & Mary’s
• Dana Lambert, PhD, President & CEO of Andira Pharmaceuticals
• Shaun Land, President & CEO of Irvine Labs

 

Together, they explored what it truly takes to develop cannabis into pharmaceutical-grade products; from rigorous R&D and regulatory navigation to breakthrough innovations in safety, delivery, and formulation.

 

For anyone invested in the therapeutic future of cannabis – patients, researchers, regulators, or purpose-driven brands – this conversation delivered a clear message: the future of cannabis as medicine is already in motion.

Key Takeaways

 

1. The Path to Pharma Is Real and Growing

• Several panelists are already deep into the pharmaceutical pathway with cannabinoid-based drugs aimed at unmet medical needs; like superbug infections, breast cancer, Parkinson’s, sleep disorders, and atopic dermatitis.

• Companies like Andira Pharmaceuticals under Dana’s leadership are taking isolated cannabinoids through FDA drug approval processes, leveraging programs like Breakthrough Therapy Designation and Qualified Infectious Disease Product status to fast-track development. But as Duncan with Bud & Mary’s emphasized, there are several pathways to take and opportunities to take more than one in this moving, shifting regulatory landscape.

• Panelists echoed that pharma-level R&D is more achievable than many believe, especially with growing regulatory familiarity and a rising number of FDA cannabinoid precedents (like dronabinol/Marinol).

 

2. Innovation in Safety and Delivery Is Catching Up

• Safety was a recurring theme, especially for immunocompromised patients. Jim with VIST Labs emphasized the need for sterilized, pathogen-free inhalable cannabis, calling out widespread contamination risks in current markets.

• Sterile post-harvest packaging, modified atmosphere technology, and cryogenic vapor sterilization are tools being adopted to ensure that cannabis meets the standards of inhaled therapeutics.

• On the delivery side, panelists discussed new formulations (gels, powders, and emulsions) that improve bioavailability and can be targeted to specific organs.

 

3. Intellectual Property (IP) Is Fueling the Future

• Companies are investing heavily in IP; particularly in formulations, delivery systems, and novel combinations of cannabinoids and other plant compounds.

• Panelists emphasized that IP isn’t just a defensive strategy; it’s the core of valuation and acquisition potential. Some companies are already filing globally and protecting multi-layered innovation stacks.
• Shaun with Irvine Labs emphasized that even if a product is not patentable, it is often still worth bringing it to market; so don’t let fear stop you from bringing a worthy product to patients who would benefit. 

 

4. Cannabis as Medicine Requires Clean Labels, Accurate Dosing

• There’s a growing awareness that inconsistent labeling and oxidation of cannabinoids can mislead patients and degrade therapeutic potential.

• Modified atmosphere packaging, common in the food industry, was suggested as a necessary next step for cannabis producers to ensure stability and truth-in-labeling, especially for products sitting on dispensary shelves for months.

 

5. Wellness, Pharma, and the “Blue Ocean” in Between

• While pharma is the ultimate gold standard, several speakers highlighted the vast potential between wellness and prescription-grade therapeutics.

• From functional edibles with therapeutic benefits to collaborations with nutrition giants, the wellness sector could be a key stepping stone to mainstream adoption.

• Tech platforms like Kanavos Inc. under Steve’s leadership are building semantic AI tools to make scientific data on cannabinoids more accessible to prescribers, patients, and regulators alike.

What We’re Excited About at Realm of Caring

 

• Elevated Safety Standards: It’s clear the industry is moving toward cleaner, more consistent products that put patient health first, something Realm of Caring has long advocated for.

• New Drug Candidates: Realm of Caring has conducted rigorous, observational research for nearly a decade; studies that pave the way for clinical trials. With more clinical trials underway for cannabinoid-based treatments in infection control and cancer, we are hopeful about expanded therapeutic options backed by rigorous data.

• Patient-First Innovation: Beyond the science, what resonated most was the shared commitment to solving real problems for real people; especially those failed by current options.

Looking Ahead

 

Realm of Caring remains dedicated to supporting research, elevating patient voices, and advocating for regulatory and product standards that reflect the true potential of cannabis as medicine. As Sasha shared in the panel, “This is the conversation for anyone serious about the future of cannabis as medicine.”

 

We’re thrilled to be part of it and we invite all patients, caregivers, researchers, and innovators to join us as we push toward a future where quality, access, and efficacy are non-negotiable.

 

To watch the full panel discussion, see the video here. 

Creatine is having a moment, and for a good reason. Backed by decades of research, it has become a staple for athletes as well as anyone seeking improved cognitive and physical performance. But there are other natural compounds making waves in the wellness world, which make up the cannabis plant. 

 

While they work differently in the body, creatine and cannabis share surprising common ground. And, more importantly, both remind us that health is not about a singular “miracle cure”, but about layering multiple tools that can support our entire, internal systems. 

 

 

The “Brain Boosters”: Cognitive and Mental Health Benefits

 

 

Creatine plays a role in providing energy through the creatine kinase (CK) and phosphocreatine (PCr) system. Several studies pointed to supplementation of creatine to assist with mental fatigue through improving cognition, executive function, and/or memory. Initial trials and few observational studies point to the alteration of depression-like behaviors with creatine supplementation. 

 

One of the major cannabinoids found in the cannabis plant, cannabidiol (CBD), has gained the attention of the research community when it comes to influence on brain function. Recent research suggests that CBD use for those with pathological conditions may see improved cognitive processes. This includes improved attention, executive function, working memory, and episodic memory.

 

For neurodegenerative diseases, CBD has shown to be a promising therapeutic agent. Several studies point to the ability of CBD to inhibit progression of Alzheimer’s disease. Although the mechanisms of the neuroprotective effects have not fully been discovered, research points to CBD’s role in reducing neuroinflammation, reducing oxidative stress, and improving cognitive performance by preventing the development of social recognition deficit.

 

Higher resting hippocampal blood flow is associated with better memory performance. Results were published in 2020 from a randomized, crossover, double-blind study where 15 healthy participants were administered oral CBD to assess how CBD influences cerebral brain flow in regions involved with memory processing. Their findings suggest that CBD does increase cerebral brain flow to the key regions involved in memory processing, particularly in the hippocampus.

 

Data indicate that repeated administration of CBD may produce an effect that is consistent with results from studies testing traditional anti-anxiety and antidepressant medications. These are known to be clinically relevant findings as CBD is known to benefit while exhibiting few side effects, supporting the initiation of clinical trials testing the efficacy of CBD-based compounds for the treatment of mood disorders. 

 

The serotonergic mechanism of CBD is distinct from commonly used antidepressant medications in that it does not appear to produce symptoms of withdrawal. CBD has also been shown to synergize with other serotonergic medications. Data suggests that CBD could facilitate the antidepressant effect induced by these antidepressant drugs, therefore allowing the SSRIs to be administered at lower doses, resulting in fewer side effects. 

 

In a recently published observational study, it was found that medicinal cannabis use was associated with lower self-reported depression. Initiation of medicinal cannabis during the follow-up period was associated with significantly decreased anxiety and depressive symptoms, an effect that was not observed in Controls who had not initiated cannabis use.

 

“Brain Booster” Takeaway: Both creatine and cannabinoids from the cannabis plant continue to be studied for their benefit to neurodegenerative conditions and improving quality of life for high-stress environments that can impact cognitive function and mental health. 

 

 

Performance and Recovery: From Gym Gains to Restorative Sleep

 

 

As we age, we are susceptible to losing strength, muscle mass, and bone mass while increasing body fat. Several studies performed in older adults, older men, and postmenopausal women suggest that creatine supplementation may promote gains in muscle mass and strength as well as bone density. A recent meta-analysis on the effects of creatine supplementation on body composition found that it may help maintain muscle mass while promoting fat mass loss.

 

When understanding the effects of creatine on sleep, a study published in 2006 reported that sleep-deprived participants better maintained random movement generation, time to react to choices, mood state, and balance when using creatine supplements. 

 

For recovery, CBD is looked to for anti-inflammatory, reducing oxidative stress, and decreasing muscle soreness. Cannabigerol (CBG) and Cannabidiolic acid (CBDA) may also offer potent anti-inflammatory and analgesic effects to promote healing post-workout. These benefits may also lead to improved sleep, by limiting stress-induced inflammation and pain. 

 

Cannabinoids cannabinol (CBN), delta-9-tetrahydrocannabinol (THC) are cannabinoids more often regarded for their sleep-promoting benefits, which may be realized at even micro-dosed amounts. 

 

Performance and Recovery Takeaway: While creatine is more widely known for muscle building and fat loss (“gains”) several cannabinoids have been studied for their recovery benefits. Both may work together to enhance overall performance. 

 

 

Metabolic Health: Focusing on the Body’s Ability to Regulate

 

 

Evidence has rapidly accumulated over time that creatine supplementation reports to help lower cholesterol, triglycerides, reduce accumulating fat on the liver, serve as an antioxidant, enhance glycemic control, and reduce the risk of heart disease. 

 

Given studies related to creatine and glucose management, there is sufficient evidence to suggest that supplementation of creatine may enhance glucose uptake and insulin sensitivity, particularly when simultaneously initiating in an exercise program. 

 

Currently, there are very few natural pharmaceutical solutions available for the treatment of metabolic syndrome. In 2023 researchers published findings analyzing a full-spectrum cannabis oil (CBD:THC, 2:1) to understand the usefulness of cannabis in metabolic syndrome, notably for blood pressure, serum metabolic parameters, and liver damage. Their study showed data that resulted in significant improvements across several metabolic syndrome parameters in animal models fed a sucrose-rich diet. They observed lower systolic and diastolic blood pressure, decreased serum levels, improved liver abnormalities, and pain relief. 

 

Researchers in 2017 reported CBD’s impact on blood pressure in healthy humans following an oral dose of 600mg showing that increased blood pressure levels as a result of stressful situations were weakened. Over time we have seen repeated actions of acute or chronic CBD treatment in reducing the cardiovascular response to models of stress, making it known to be an anxiolytic. 

 

For diabetes prevention, tetrahydrocannabivarin (THCV) has recently been looked to for aiding weight loss. There is also research to show the promise of CBD and THCV in reducing insulin resistance and moderating blood sugars.

 

Metabolic Health Takeaway: Both creatine and cannabis compounds are showing to support metabolic regulation, a key to long-term health. 

 

 

Conclusion: Layer, Don’t Lean

 

 

Creatine isn’t the answer. Neither is cannabis. But together they reflect a modern, integrative approach to health that supports systems rather than symptoms. If you are looking to enhance performance, energy, and mood, the most sustainable approach is layering lifestyle, diet, movement, and the right supplementation for you. 

 

Curious about how to start incorporating cannabinoids into your wellness routine safely and effectively? Learn more with us at Realm of Caring.

When it comes to optimizing our health, sleep is often the unsung hero. We can drink green juice, hit the gym, and take all the right supplements; but if we’re not getting high-quality rest, our bodies (and minds) pay the price. The truth is, good sleep is foundational. It’s when our systems reset, repair, and recover. And in today’s fast-paced world, more and more people are starting to pay attention to just how well they’re sleeping.

 

The Rise of Sleep Tracking in Wellness Culture

 

Over the past few years, sleep tracking has become a growing part of the wellness conversation. Tools like the Oura Ring, WHOOP band, and other wearable devices are empowering individuals to better understand their sleep cycles, identify disruptions, and make data-informed decisions to support rest. These trackers give us a window into our nighttime behaviors – monitoring things like deep sleep, REM cycles, heart rate variability, and recovery scores.

 

This growing curiosity is no surprise. Research continues to confirm what many of us feel intuitively: better sleep leads to better days. From mood and memory to immune function and metabolic health, nearly every system in our body benefits when we rest well.

 

Hemp Edibles: A Natural Tool for Deeper Sleep

 

For those struggling with falling or staying asleep, hemp-derived edibles may offer a natural and effective solution. Many individuals report that cannabinoids like CBD, CBN, and even low-dose THC help calm the nervous system and promote a sense of relaxation before bed. Unlike traditional sleep aids that can leave you groggy or dependent, hemp extract edibles may support sleep with fewer side effects, especially when used mindfully and under the guidance of a healthcare professional.

 

In addition to improving sleep quality, edibles may support overnight recovery, particularly when paired with a healthy lifestyle. For individuals who are active, managing stress, or recovering from illness or injury, this added benefit is a game-changer. Some cannabinoids have anti-inflammatory properties, which may enhance the body’s repair processes during deep sleep.

 

Understand what non-cannabis ingredients are added

 

Many edible products will have a few other ingredients other than the cannabinoids from hemp oil to include a carrier oil (to assist with absorption), natural flavoring, gelling agents (for edible gummies), natural coloring, and/or citric acid (preservative. However, you may recall advertisements for CBD products that promote “best for sleep”. Typically, these claims can be made if: (a) Research supports the claim for the specific cannabinoid or (b) The product includes an ingredient, other than what has been listed above, which has been researched to affect the normal functioning of the body in that way. 

 

If a CBD product is labeled for sleep, then it may include Melatonin, L-theanine, or Valerian Root. CBD has researched sleep benefits of its own, but may work synergistically with these added ingredients for an additional boost. Before purchasing, understand what ingredients have been added and if those are right for you.

 

A Trusted Source for Sleep Support

 

At Realm of Caring, we understand how overwhelming the hemp and cannabis marketplace can feel, especially when you’re seeking products for something as personal and essential as sleep. That’s why our care team is here to offer free support and we’ve partnered with Bonni Goldstein Wellness to provide you a curated marketplace of lab-tested hemp extract products trusted by some of the most experienced cannabis clinicians in the U.S.

 

Find sleep-specific edible products that contain cannabinoids known to support rest, all vetted for purity, potency, and transparency. As a Realm of Caring client, you’ll receive free options to make your therapy more affordable, so get in touch to find out more. 

 

Whether you’re new to using cannabis for sleep or looking for a more consistent solution, we’re here to support you with trusted education and quality products.

 

Ready to Sleep Smarter?

 

Better sleep starts with informed choices for your overall well-being. Realm of Caring is here to help with research backed information, facilitating conversations with your doctor, and individualized support. 

An estimated 1 in 5 people will experience hives, also known as urticaria, at some point in their lives. For many, it is a temporary inconvenience. For others, it is a recurring, distressing condition. With symptoms like itching, burning, swelling, and redness, allergic responses like hives can interfere with daily life, sleep, and overall well-being. As interest in plant-based therapies grows, researchers and consumers alike are turning to CBD and other cannabinoids as potential alternatives to traditional antihistamines and steroid creams.

 

But what does the science say about using cannabis for hives, rashes, and other allergy-related symptoms?

 

What Are Hives, and What Causes Them?

 

Hives are welts or raised bumps on the skin that appear suddenly due to an allergic reaction, stress, infection, or other unknown triggers. They’re categorized into two main types:

 

• Acute Urticaria – Lasts less than 6 weeks

 

• Chronic Urticaria – Occurs nearly daily and persists for more than 6 weeks

 

 

Common symptoms include:

 

• Intense itching

 

• Red or skin-colored welts

 

• Swelling of the face, lips, or throat in severe cases

 

• In rare instances: joint pain, fever, or gastrointestinal upset

 

While antihistamines and topical steroids are typically prescribed, they don’t always bring relief and they can cause unwanted side effects such as drowsiness or thinning skin.

 

How the Endocannabinoid System (ECS) Plays a Role

 

The human body has an endocannabinoid system (ECS), which helps regulate immune response, inflammation, skin health, and more. This system includes receptors (CB1 and CB2) found in the brain, immune cells, and skin tissue.

 

Research suggests that imbalances in the ECS may contribute to chronic inflammatory skin conditions, including eczema and urticaria. By interacting with the ECS, cannabinoids like cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) may help restore balance and reduce inflammation.

 

What Does the Research Say?

 

Anti-Inflammatory Effects

Several published studies confirm that CBD has significant anti-inflammatory properties. This is particularly relevant for hives and rashes, where inflammation drives most of the symptoms.

 

Skin Barrier Protection

CBD has also been shown to support skin barrier repair and modulate the immune system locally when applied topically. A 2019 study in La Clinica Terapeutica found that CBD-enriched ointment significantly improved skin parameters (hydration, elasticity, inflammation) in patients with chronic skin disorders. 

 

THC, CBG, and CBN

While CBD gets most of the spotlight, other cannabinoids including THC, cannabigerol (CBG), and cannabinol (CBN) also show promise. THC’s interaction with CB2 receptors in immune cells may help suppress hypersensitive immune responses, which is central to allergic flare-ups. A 2013 study showed that the topical treatment of THC for mice with dinitrofluorobenzene (DNFB)-mediated allergic contact dermatitis effectively reduced immune cell infiltration and decreased allergic ear swelling

 

Immune System Modulation

In preclinical studies, cannabinoids have demonstrated the ability to suppress mast cell activation (the immune cells responsible for releasing histamine during allergic reactions). This could make cannabinoids especially useful for people with histamine intolerance or chronic hives.

 

Topical or Oral: What’s Best?

 

Topical formulations (like salves and creams) are ideal for localized skin issues. They allow cannabinoids to interact directly with skin receptors without entering the bloodstream. This can bring targeted relief without psychoactive effects, even in formulations that include THC.

 

For systemic symptoms or chronic inflammatory conditions, oral CBD or THC may provide additional support. However, onset time is slower, and administration consistency is key.

 

What to Look for in a Product

 

If you’re exploring CBD or cannabinoid-based products for allergy-related skin issues, consider:

 

• Full-spectrum formulas: These contain multiple cannabinoids and terpenes that may work synergistically (entourage effect).

 

• Third-party testing: Ensure the product is tested for potency, purity, and contaminants.

 

• Transdermal or salve: Look for products specifically designed for skin absorption.

 

Safety and Side Effects

 

CBD and other cannabinoids are generally well-tolerated. Side effects are rare and mild but can include:

 

• Skin irritation (if using low-quality or fragranced topicals)

 

• Drowsiness (if using high doses of oral cannabinoids)

 

• Interactions with other medications

 

Always consult with a healthcare provider, especially when dealing with chronic hives, autoimmune conditions, or pediatric cases. Not sure where to start? Realm of Caring care specialists are here to help. 

 

Key Takeaways

 

Cannabinoid therapy may offer meaningful relief for those experiencing hives, rashes, or allergy-related symptoms, particularly when conventional treatments fall short. With growing scientific support for its anti-inflammatory, immune-modulating, and skin-protective effects, CBD and other cannabinoids are earning a well-deserved spot in the skin health conversation.

 

In the fitness and wellness world, the key for optimal post-workout recovery has led to an exciting discovery: functional mushrooms. These powerful fungi are gaining recognition for their potential to enhance recovery, boost energy, and support overall health. Packed with vitamins, minerals, and unique compounds, functional mushrooms like lion’s mane, cordyceps, and reishi are making waves in the athletic community for their ability to aid muscle recovery and reduce stress.

 

Functional mushrooms impact various aspects of recovery, from reducing inflammation and supporting the immune system to improving sleep quality and enhancing endurance. This article will explore the benefits of functional mushrooms for post-workout recovery, examine the science behind their effectiveness, and provide practical tips to incorporate these super fungi into your fitness regimen.

 

Post-Workout Recovery Essentials

 

Effective post-workout recovery is crucial for athletes and fitness enthusiasts to maintain performance and prevent injuries. It involves several key components that work together to help the body repair, recharge, and prepare for future workouts.

 

Muscle Repair

 

After intense physical activity, muscles experience microscopic damage that needs repair. This process is essential for muscle growth and adaptation. Functional mushrooms may play a significant role in supporting muscle repair:

 

1. Antioxidant support: Mushrooms like turkey tail, lion’s mane, and reishi are rich in antioxidants that could help neutralize harmful reactive oxygen species generated during exercise. These antioxidants resist oxidative stress and protect cells from damage caused by intense workouts.
2. Protein synthesis: Consuming adequate protein after exercise is crucial for muscle repair. While mushrooms are not high in protein, they can complement a protein-rich post-workout meal to support overall recovery.

 

Inflammation Reduction

 

Exercise-induced inflammation is a natural part of recovery, but excessive inflammation can hinder progress. Functional mushrooms have potential for anti-inflammatory properties:

 

1. Chaga mushrooms: Rich in antioxidants, chaga could helps lower inflammation and aids in muscle growth and tissue regeneration.
2. Reishi mushrooms: Known for their anti-inflammatory effects, could help manage oxidative stress and fight fatigue symptoms.
3. Turkey tail mushrooms: These fungi may limit the production of inflammatory compounds like COX-2, potentially speeding up the restructuring of ligaments, tendons, and connective tissues.

 

Energy Restoration

 

Replenishing energy stores is vital for post-workout recovery and preparation for future training sessions. Functional mushrooms may contribute to energy restoration in several ways:

 

1. Cordyceps: This mushroom may impacts oxygen absorption, potentially enhancing endurance and relieving sore muscles during recovery. Studies have shown that cordyceps can increase endurance and reduce fatigue after one week.
2. Reishi: Known for its adaptogenic properties, reishi may help the body cope with stress and regulate physiological functions. It has also been shown to reduce lactic acid in the body, promoting better recovery.
3. Antrodia mushrooms: These fungi may improve muscular strength and upregulate “anti-fatigue factors,” potentially improving metabolic efficiency and sparing muscle glycogen.

 

By incorporating functional mushrooms into post-workout routines, athletes and fitness enthusiasts may enhance their recovery process, reduce muscle soreness, and prepare their bodies for future training sessions.

 

Adaptogenic Effects

 

Certain mushroom species possess adaptogenic properties, helping the body respond to stress, anxiety, and fatigue. Cordyceps, in particular, has a long history of traditional use and is gaining recognition in modern wellness for its potential contributions to human health. Studies suggest that Cordyceps is an effective adaptogen, supporting the body’s ability to adapt to physical and mental stressors.

 

Reishi mushrooms are also known for their adaptogenic effects. They impact the body’s adaptation to mental and physical stressors, making them valuable for post-workout recovery. Potentially helping the body manage stress more effectively, these mushrooms can contribute to faster recovery times and improved overall performance.

 

Immune System Support

 

Intense training and exercise can temporarily suppress the immune system, making athletes more susceptible to infections. Functional mushrooms may boost immune health during recovery periods.

 

Certain mushroom species, such as Cordyceps, reishi, and turkey tail, have been studied for their potential immune-modulating properties. Including these mushrooms in the diet or using mushroom extracts could support healthy immune function. For example, reishi has been shown to stimulate the activity of various immune cells, including natural killer (NK) cells and macrophages.

 

A study published in the British Journal of Sports Medicine observed that using reishi mushrooms in healthy football players provided immune support when exposed to stressful workouts and a low-oxygen environment. This particularly benefits athletes who are often susceptible to upper respiratory tract infections due to intense training and competition.

 

Incorporating Functional Mushrooms into Your Post-Workout Routine

 

To maximize the benefits of functional mushrooms for post-workout recovery, it is essential to understand the optimal timing, dosage, and potential combinations with other supplements.

 

Timing of Consumption

 

The timing of functional mushroom consumption can significantly impact their effectiveness in supporting recovery. For instance, cordyceps, known for its energy-boosting properties, can be taken before or after a workout:

1. Pre-workout: Taking cordyceps before exercise can help boost energy levels and enhance performance.
2. Post-workout: Consuming cordyceps after exercise may aid in post-workout recovery.

It is often recommended to avoid taking cordyceps late in the evening, as it may increase alertness and disrupt sleep.

 

Conclusion

 

Functional mushrooms have shown promising potential to enhance post-workout recovery, offering a range of benefits for athletes and fitness enthusiasts. These powerful fungi impact various aspects of recovery, including muscle repair, inflammation reduction, and energy restoration. Their antioxidant properties, adaptogenic effects, and immune system support make them valuable allies for optimal performance and faster recovery times.

 

To make the most of functional mushrooms, consider the timing of consumption, proper dosage, and potential combinations with other supplements. By incorporating these natural powerhouses into post-workout routines, athletes may speed up recovery, reduce muscle soreness, and maintain a strong immune system. This allows for consistent training and improved overall performance, making functional mushrooms a game-changing addition to any fitness regimen.

 

 To learn more, reach out to a Realm of Caring Care Specialist, visit Unlimited Sciences, or head to Lily’s Lighthouse. 

Cannabis & Mental Health: The Science Is Still Out

 

As mental health challenges rise across all age groups, more people are turning to alternative therapies, including cannabis. But is cannabis a tool for healing, or could it do more harm than good? The truth is, the science is still out, and we at Realm of Caring believe it’s essential to slow down, zoom in, and listen both to the research and to our internal selves.

 

What the Research Currently Says

 

• Mixed outcomes dominate the literature.
  While some studies suggest cannabis may offer temporary relief for anxiety, PTSD, and depression, others show it can exacerbate symptoms, especially in high doses or among individuals predisposed to mood disorders. 
• CBD and THC affect the brain differently.
  Cannabidiol (CBD) has been linked to anxiolytic (anxiety-reducing) effects in several small studies. Tetrahydrocannabinol (THC), on the other hand, may temporarily increase anxiety and paranoia at high doses, particularly in those who are not accustomed to it. 
• Long-term studies are lacking.
  We still don’t fully understand the long-term impact of regular cannabis use on mental health. More clinical trials, especially those focused on patient-reported outcomes, are needed. If you want to contribute to change first hand, consider joining our Observational Research Study. 

The Importance of Intention

 

“If you’re not in a space to set an intention before you use, don’t use.”

 

We’ve heard this from clinicians, caregivers, and cannabis patients alike and we stand by it. Using cannabis with a clear, grounded intention can make all the difference in outcomes.

 

Ask yourself:

 

• Am I using this to escape or to support healing? 
• Do I understand the product I’m using and how it might affect me? 
• Am I integrating other forms of support – like therapy, rest, or movement?

 

When cannabis is used impulsively, especially in moments of desperation, it can act more like a band-aid than a balm. We encourage mindfulness over urgency.

 

Caution in Moments of Desperation

 

Cannabis is not a replacement for crisis care.

 

• If you’re in a mental health crisis, cannabis should not be your first line of defense.
  It’s not a rescue medication. It can sometimes worsen intrusive thoughts, dissociation, or feelings of helplessness in the short term. 
• Reach out to a qualified mental health provider.
  If you’re feeling unsafe, overwhelmed, or unsure, talk to someone. Cannabis might be a part of your wellness toolkit later, but only once you’ve stabilized.

 

Legalization ≠ Medicine

 

In today’s cannabis market, it’s easy to mistake access for approval.

 

• Just because it’s legal doesn’t mean it’s safe (or right) for everyone.
  Many cannabis products are formulated for recreation, not precision. Potency, purity, and consistency vary widely. Without medical oversight, you’re essentially self-prescribing. 
• We need to bring the conversation back to medicine.
  The medicinal potential of cannabinoids is real, but so is the need for regulation, research, and education. Patients deserve access to tested, reliable products and practitioners who understand cannabinoid therapeutics.

 

Moving Forward: What We Believe

 

At Realm of Caring, we advocate for a future where:

• Research is funded and prioritized. 
• Patient voices are central to policy and product development. 
• Cannabis is seen not as a miracle cure, but as one tool among many. 

 

If you’re considering cannabis for mental health support:

 

• Start low and go slow. 
• Use a product with a known cannabinoid profile. 
• Track how you feel over time. 
• Stay connected to your care team.

 

Final Thoughts

 

Cannabis can offer support but it’s not a silver bullet, especially when it comes to mental health. Whether you’re navigating anxiety, depression, PTSD, or stress, the most powerful tool you have is knowledge.

Stay informed. Stay intentional. And most importantly, stay safe.