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Featured Articles: Realm of Caring's Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023
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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022
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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021
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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021
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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020
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Rare but relevant: Cannabis use and myocardial infarction


Abstract Pre-clinical research and case reports have linked cannabis use to myocardial infarction (MI) since the 1970s. The association with MI may be specific to

November 20, 2025


Rare but relevant: Cannabinoid hyperemesis syndrome


Please use this link to access this publication. Abstract Cannabinoid hyperemesis syndrome (CHS) is a (probably) rare syndrome that occurs in frequent and chronic cannabis

February 1, 2026


Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs


OBJECTIVE To determine the safety and pharmacokinetics of various doses of plant- derived cannabidiol (CBD) versus placebo following repeated oral administration. ANIMALS 20 healthy adult

October 28, 2021


Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis


Background: Central pain in multiple sclerosis (MS) is common and often refractory to treatment. Methods: We conducted a single-center, 5-week (1-week run-in, 4-week treatment), randomized,

September 19, 2019


Randomized Placebo-Controlled Double-Blind Clinical Trial of Cannabis-Based Medicinal Product (Sativex) in Painful Diabetic Neuropathy: Depression is a major confounding factor


OBJECTIVE To assess the efficacy of Sativex, a cannabis-based medicinal extract, as adjuvant treatment in painful diabetic peripheral neuropathy (DPN). RESEARCH DESIGN AND METHODS In

October 7, 2024


Randomized Laboratory Study of Single-Dose Cannabis, Dronabinol, and Placebo in Patients With Schizophrenia and Cannabis Use Disorder Get access Arrow


Please use this link to access this publication. Abstract Background and Hypothesis Up to 43% of people with schizophrenia have a lifetime cannabis use disorder

September 5, 2024


Randomized controlled trials on the use of cannabis-based medicines in movement disorders: a systematic review


Please use this link to access this publication. Abstract Anecdotal references, preclinical, and non-randomized studies support the therapeutic potential of cannabinoids for movement disorders (MD).

March 14, 2024


Randomized blinded controlled clinical trial to assess the effect of oral cannabidiol administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with intractable idiopathic epilepsy


Abstract OBJECTIVE To assess the effect of oral cannabidiol (CBD) administration in addition to conventional antiepileptic treatment on seizure frequency in dogs with idiopathic epilepsy.

January 11, 2024


Racial and Ethnic Differences in Cannabis Use Following Legalization in US States With Medical Cannabis Laws


Key Points Question  Is the legalization of recreational cannabis in the US associated with changes in cannabis use outcomes and cannabis use disorder across racial and

October 7, 2024


Quarterly trends in past-month cannabis use in the United States, 2015-2019


Please use this link to access this publication. Abstract Background Prevalence of cannabis use has been increasing among select subgroups in the US; however, trend

May 17, 2025


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