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  • ∆9-tetrahydrocannabinol (THC), Cannabidiol (CBD), CBD oil, drug test
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Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

Recent studies have shown that even low amounts of D9-tetrahydrocannbinol (THC) within a cannabidiol (CBD) product can result in positive 11-nor-9-carboxy-D9- tetrahydrocannabinol (THC-COOH; a metabolite of THC) urine drug screens. One study reported positive drug screening in 2/6 participants after acute administration of vaporized CBD-dominant cannabis flower (10.5% CBD; 0.39% THC) using liquid chromatography tandem mass spectrometry (LC-MS/MS; which distinguishes between THC-COOH and other cannabinoids/metabolites) at a criterion of greater than or equal to 15 ng/mL THC-COOH. Another study found that 7/14 patients who used a hemp-derived CBD extract (0.02% THC) for 4 weeks yielded positive 50 ng/mL drug screens, 6 of which were...
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Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs

Osteoarthritis (OA) is the most common chronic condition that dogs face. If diagnosed, it is important to focus on managing the symptoms versus find a cure. This study shows that cannabidiol (CBD) can help increase comfort and activity levels in dogs with OA. Objectives: The objectives of this study were to determine basic oral pharmacokinetics, and assess safety and analgesic efficacy of a cannabidiol (CBD) based oil in dogs with osteoarthritis (OA). Methods: Single-dose pharmacokinetics was performed using two different doses of CBD enriched (2 and 8 mg/kg) oil. Thereafter, a randomized placebo-controlled, veterinarian, and owner blinded, cross-over study was conducted. Dogs received each...
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