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What Schedule III Means for Cannabis – And What Comes Next

  • December 18, 2025
Schedule III Cannabis

What Schedule III Means for Cannabis – And What Comes Next

Following today’s announcement from the White House, federal cannabis policy appears poised for a meaningful shift. President Trump has indicated his administration’s intent to move cannabis toward a Schedule III posture under the Controlled Substances Act. While this signals progress and marks a significant federal shift and a long-awaited acknowledgment that cannabis has accepted medical use, it is important to be clear: an Executive Order does not immediately reschedule cannabis and it is not a comprehensive solution.

 

What Schedule III Means

 

Schedule III substances are recognized as having medicinal value and a lower potential for misuse compared to Schedule I or II substances. Moving cannabis into this category brings federal policy closer to the reality that millions of Americans already experience: cannabinoid therapies are being used every day to support health, comfort, and quality of life.

 

This rescheduling creates several important opportunities:

 

  • Federal recognition of medical use
    Cannabis is no longer classified alongside substances deemed to have no accepted medical value. This acknowledgment reduces stigma and affirms decades of patient experience and emerging scientific evidence. 
  • Expanded research potential
    Schedule III status lowers administrative and regulatory barriers that have historically limited cannabis research. This change may accelerate studies on safety, efficacy, dosing, and long-term outcomes, particularly for vulnerable populations such as older adults. 
  • A pathway toward federal safety standards
    Rescheduling makes it possible to develop clearer federal expectations around product quality, including manufacturing practices, laboratory testing, labeling accuracy, and consumer protections. These guardrails have been largely absent despite widespread use. 
  • Greater alignment with real-world use
    Federal policy is now more closely aligned with how cannabis and cannabinoid products are already being used to manage pain, sleep challenges, inflammation, anxiety, and other conditions.

 

What Schedule III Does Not Do

 

While meaningful, rescheduling does not resolve many of the structural challenges patients still face.

 

This change does not:

 

  • Legalize cannabis at the federal level 
  • Replace or standardize state medical cannabis programs 
  • Guarantee patient access across state lines 
  • Establish a national medical cannabis framework 
  • Ensure affordability, insurance coverage, or provider participation 

 

In other words, rescheduling is an opening, not a finish line. Without additional federal action, patients and providers may continue navigating a fragmented system with uneven access and inconsistent protections.

 

What Happens Next

 

Rescheduling cannabis requires an administrative sequence, not a single action. The Department of Justice must still conduct a formal rulemaking process, which includes scientific and medical evaluation, interagency consultation, public notice, and the opportunity for legal challenge.

 

Why This Moment Matters

 

Today’s announcement reflects years of sustained advocacy that reframed cannabis from a political liability to a public health issue. It changes the conversation and the expectations inside Washington.

This is a moment to recognize progress while staying focused on substance over headlines. The durability of this shift will depend on what is written into policy, how agencies are instructed to act, and whether timelines and safeguards survive scrutiny.

 

Realm of Caring will continue to engage at every stage of this process through conducting research, educating patients, providers and industry, and advocating for a regulatory pathway that prioritizes safety, evidence, and access. This moment matters not because it finishes the work, but because it makes the next phase possible.

 

Stay up to date here: www.realmofcaring.org/save-hemp/

 

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