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Research Library

Realm of Caring's Latest Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023

Recent studies have shown that even low amounts of D9-tetrahydrocannbinol (THC) within a cannabidiol (CBD) product can result in positive 11-nor-9-carboxy-D9- tetrahydrocannabinol (THC-COOH; a metabolite of THC) urine drug screens.

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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022

Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis users.   Methods: An anonymous online survey collected demographics, health information, and open-ended responses from medicinal cannabis users regarding perceptions, motivations,

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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021

Background: Anxiety and depressive disorders are highly prevalent. Patients are increasingly using medicinal cannabis products to treat these disorders, but little is known about the effects of medicinal cannabis use on

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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021

Abstract:    Recent approval of Epidiolex (pharmaceutical cannabidiol/CBD) for the treatment of Lennox Gastaut syndrome (LGS) and Dravet syndrome highlights a therapeutic efficacy of CBD in the treatment of epilepsy.

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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020

Introduction. Despite widespread legalization, the impact of medicinal cannabis use on patient level health and quality of life has not been carefully evaluated. The objective of this study was to

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Use of Cannabis-Based Medical Products for Pediatric Health Conditions: A Systematic Review of the Recent Literature


Abstract Introduction: Cannabis policy is rapidly changing in the USA and across the globe, with 24 states legalizing cannabis for adult use and 38 states making medical cannabis available for those […]

February 27, 2025


Use of Cannabis to Relieve Pain and Promote Sleep by Customers at an Adult Use Dispensary


Abstract Medical cannabis patients consistently report using cannabis as a substitute for prescription medications; however, little is known about individuals accessing cannabis through adult-use markets. A survey at two retail […]

November 22, 2023


Use of Cannabis in Fetal Alcohol Spectrum Disorder


Please use this link to access this publication. Abstract Background: Fetal alcohol spectrum disorder (FASD) has been recently estimated to afflict up to 5% of American children. Most of these children […]

November 4, 2024


Use of Cannabis for Self-Management of Chronic Pelvic Pain


Please use this link to access this publication. Abstract Background: Chronic pelvic pain (CPP) affects up to 15% of women in the United States. The endocannabinoid system is a potential pharmacological […]

June 7, 2025


Use of cannabis for mental health in the Canadian territories: a cross-sectional study


Please use this link to access this publication. Abstract Background Population prevalence and patterns of cannabis use for mental health (CUMH) are underexplored. This is important to understand in the […]

December 4, 2024


Use of Cannabis for Harm Reduction Among People at High Risk for Overdose in Vancouver, Canada (2016–2018)


Please use this link to access this publication. Abstract Objectives. To characterize the prevalence and reasons for the use of cannabis as a strategy to reduce the harms arising from other […]

July 18, 2025


Use of Cannabis as a Harm Reduction Strategy Among People Who Use Drugs: A Cohort Study


Please use this link to access this publication: https://www.liebertpub.com/doi/full/10.1089/can.2021.0229 Abstract Introduction: While substance use contributes to a substantial burden of disease, access to evidence-based harm reduction interventions remains limited or inaccessible. Preliminary […]

November 29, 2023


Use of Cannabis and Other Pain Treatments Among Adults With Chronic Pain in US States With Medical Cannabis Programs



Use of Cannabis and Cannabinoids in Patients With Cancer


Please use this link to access this publication. Abstract Objective: To review pharmacology, available dosage forms, efficacy, and safety of cannabis and cannabinoids in cancer patients. Data Sources: In PubMed […]

October 3, 2024


Use of Cannabis and Cannabinoids for Treatment of Cancer


Abstract The endocannabinoid system (ECS) is an ancient homeostasis mechanism operating from embryonic stages to adulthood. It controls the growth and development of many cells and cell lineages. Dysregulation of […]

February 29, 2024


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