Specific phytocannabinoid compositions are associated with analgesic response and adverse effects in chronic pain patients treated with medical cannabis

Please use this link to access this publication. Abstract Medical cannabis (MC) treatment for chronic pain is increasing, but evidence regarding short- and long-term efficacy and

May 30, 2024

Specific Compositions of Cannabis sativa Compounds Have Cytotoxic Activity and Inhibit Motility and Colony Formation of Human Glioblastoma Cells In Vitro

Abstract Glioblastoma multiforme (GBM) is the most lethal subtype of glioma. Cannabis sativa is used for the treatment of various medical conditions. Around 150 phytocannabinoids have been

August 21, 2025

Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands

Cannabinoids, endocannabinoids and marijuana activate two well-characterized cannabinoid receptors (CB-Rs), CB1-Rs and CB2-Rs. The expression of CB1-Rs in the brain and periphery has been well

September 19, 2019

Spanish versions and validation of a series of rating scales and visual analogue scales to assess the subjective effects of cannabis

Please use this link to access this publication. Abstract Cannabis is being legalized for medical and recreational purposes all around the world. However, the understanding

March 7, 2026

Sociodemographic Characteristics Associated With and Prevalence and Frequency of Cannabis Use Among Adults in the US

Abstract Importance  Cannabis use has increased, but there are few studies on frequent and daily cannabis use among US adults. Individuals who engage in higher frequency

May 11, 2025

Social Norms for Cannabis Use After Nonmedical Legalization in Canada

Please use this link to access this publication. Abstract Introduction Social norms play an important role in cannabis use; however, there is little evidence on

March 6, 2025

Social Anxiety, Cannabis Use Motives, and Social Context’s Impact on Willingness to Use Cannabis

Abstract Social anxiety is often purported to be a risk factor for increased cannabis use. Cannabis use motives are strong explanatory predictors of cannabis use

July 5, 2025

Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial

Background: Spasticity is a common and poorly controlled symptom of multiple sclerosis. Our objective was to determine the short-term effect of smoked cannabis on this

September 19, 2019

Smoked cannabis for chronic neuropathic pain: a randomized controlled trial

Abstract Background Chronic neuropathic pain affects 1%–2% of the adult population and is often refractory to standard pharmacologic treatment. Patients with chronic pain have reported

Sleep-wake cycle disturbances and NeuN-altered expression in adult rats after cannabidiol treatments during adolescence

Please use this link to access this publication. Abstract Rationale The medical uses of cannabidiol (CBD), a constituent of the Cannabis sativa, have accelerated the

April 15, 2024