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The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation
Anandamide was the first brain metabolite shown to act as a ligand of ‘‘central’’ CB1 cannabinoid receptors. Here we report that the endogenous cannabinoid potently
September 19, 2019
The Endocannabinoid-CB Receptor System: Importance for development and in pediatric disease
Abstract Endogenous cannabinoids (endocannabinoids) and their cannabinoid CB1 and CB2 receptors, are present from the early stages of gestation and play a number of vital
The endocannabinoid system, cannabis, and cannabidiol: Implications in urology and men’s health
Abstract Background: The endocannabinoid system is a neuromodulatory system responsible for partial regulation of cognitive and emotional processes in the human central nervous system such
July 11, 2025
The Endocannabinoid System, Cannabinoids, and Pain
Abstract The endocannabinoid system is involved in a host of homeostatic and physiologic functions, including modulation of pain and inflammation. The specific roles of currently
September 19, 2019
The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders
Please use this link to access this publication. Abstract The skin is the largest organ of the body and has a complex and very active
October 30, 2024
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities
The newly discovered endocannabinoid system (ECS; comprising the endogenous lipid mediators endocannabinoids present in virtually all tissues, their G-protein-coupled cannabinoid receptors, biosynthetic pathways and metabolizing
September 19, 2019
The Endocannabinoid System of Animals
Our understanding of the Endocannabinoid System of animals, and its ubiquitous presence in nearly all members of Animalia, has opened the door to novel approaches
April 7, 2020
The Endocannabinoid System Is Dysregulated in Multiple Sclerosis and in Experimental Autoimmune Encephalomyelitis
The ability of cannabinoids to modulate both inflammatory and degenerative neuronal damage prompted investigations on the potential benefits of such compounds in multiple sclerosis (MS)and
September 19, 2019
The endocannabinoid system in obesity and type 2 diabetes
Endocannabinoids (ECs) are defined as endogenous agonists of cannabinoid receptors type 1 and 2 (CB1 and CB2). ECs, EC anabolic and catabolic enzymes and cannabinoid
The endocannabinoid system in normal and pathological brain ageing
The role of endocannabinoids as inhibitory retrograde transmitters is now widely known and intensively studied. However, endocannabinoids also influence neuronal activity by exerting neuroprotective effects
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