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The Grass Might Be Greener: Medical Marijuana Patients Exhibit Altered Brain Activity and Improved Executive Function after 3 Months of Treatment
Abstract The vast majority of states have enacted full or partial medical marijuana (MMJ) programs, causing the number of patients seeking certification for MMJ use
November 15, 2023
The Genetic Structure of Marijuana and Hemp
Abstract Despite its cultivation as a source of food, fibre and medicine, and its global status as the most used illicit drug, the genus
September 1, 2022
The Expression Level of CB1 and CB2 Receptors Determines Their Efficacy at Inducing Apoptosis in Astrocytomas
Background: Cannabinoids represent unique compounds for treating tumors, including astrocytomas. Whether CB1 and CB2 receptors mediate this therapeutic effect is unclear. Principal Findings: We generated
September 19, 2019
The Exploration of Cannabis and Cannabinoid Therapies for Migraine
Please use this link to access this publication. Abstract Purpose of review: There is increasing interest in the use of cannabis and cannabinoid therapies (CCT) by
September 5, 2024
The Evolving Role of Cannabidiol-Rich Cannabis in People with Autism Spectrum Disorder: A Systematic Review
Abstract Autism spectrum disorder (ASD) is a neurological disease and lifelong condition. The treatment gap in ASD has led to growing interest in alternative therapies,
December 17, 2024
The endogenous cannabinoid, anandamide, induces COX-2- dependent cell death in apoptosis-resistant colon cancer cells
Despite recent advances in understanding colorectal tumour biology, there is still a need to improve the 5-year survival rate of patients with colorectal cancer as
September 19, 2019
The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2
Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandinethanolamides (PG-EAs).
The Endogenous Cannabinoid System Stimulates Glucose Uptake in Human Fat Cells via Phosphatidylinositol 3-Kinase and Calcium Dependent Mechanisms
Background: The endogenous cannabinoid system participates in the regulation of energy balance, and its dysregulation may be implicated in the pathogenesis of obesity. Adipose tissue
The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy
Several lines of evidence suggest that cannabinoid compounds are anticonvulsant. However, the anticonvulsant potential of cannabinoids and, moreover, the role of the endogenous cannabinoid system
The Endogenous Cannabinoid System and Its Role in Nociceptive Behavior
Abstract The analgesic properties of exogenous cannabinoids have been recognized for many years and suggest a regulatory role for the endogenous cannabinoid (“endocannabinoid”) system in
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