The Pharmacological Basis of Cannabis Therapy for Epilepsy

Recently, cannabis has been suggested as a potential alternative therapy for refractory epilepsy, which affects 30% of epilepsy, both adults and children, who do not

September 19, 2019

The Pharmacologic and Clinical Effects of Medical Cannabis

Cannabis, or marijuana, has been used for medicinal purposes for many years. Several types of cannabinoid medicines are available in the United States and Canada.

The pharmacokinetics, efficacy, and safety of a novel selective-dose cannabis inhaler in patients with chronic pain: A randomized, double-blinded, placebo-controlled trial

Abstract Background Precise cannabis treatment dosing remains a major challenge, leading to physicians’ reluctance to prescribe medical cannabis. Objective To test the pharmacokinetics, analgesic effect,

July 2, 2024

The Pharmacokinetics and Pharmacodynamics of a Hemp-Derived “Full-Spectrum” Oral Cannabinoid Product with a 1:1 Ratio of Cannabidiol to Cannabidiolic Acid and Delta-9-Tetrahydrocannabinol to Delta-9-Tetrahydrocannabinolic Acid: A Double-Blind, Placebo-Controlled, Within-Subjects Human Laboratory Study

Abstract Aim: To examine the acute pharmacokinetics (PK) and pharmacodynamics (PD) of a patented oral cannabinoid product containing a botanical hemp-derived “full-spectrum” extract with an

March 22, 2026

The Pharmacogenetics of Cannabis in the Treatment of Chronic Pain

Abstract Background: The increase in the medical use of cannabis has revealed a number of beneficial effects, a variety of adverse side effects and great

March 14, 2024

The Peripheral Cannabinoid Receptor Type 1 (CB1) as a Molecular Target for Modulating Body Weight in Man

Abstract The cannabinoid 1 (CB1) receptor regulates appetite and body weight; however, unwanted central side effects of both agonists (in wasting disorders) or antagonists (in

March 29, 2024

The pattern of neurodegeneration in Huntington’s disease: a comparative study of cannabinoid, dopamine, adenosine and GABAa receptor alterations in the human basal ganglia in Huntington’s disease

In order to investigate the sequence and pattern of neurodegeneration in Huntington’s disease, the distribution and density of cannabinoid CB1, dopamine D1 and D2, adenosine

September 19, 2019

The Pathophysiology and the Therapeutic Potential of Cannabinoids in Prostate Cancer

Abstract Prostate cancer is the second most frequently occurring cancer diagnosed among males. Recent preclinical evidence implicates cannabinoids as powerful regulators of cell growth and

March 29, 2024

The other side of the leaf: Seizures associated with synthetic cannabinoid use

Please use this link to access this publication. Abstract There has recently been a marked rise in the medicinal use of cannabis for epilepsy and

September 5, 2025

The orphan receptor GPR55 is a novel cannabinoid receptor

Background: The endocannabinoid system functions through two well characterized receptor systems, the CB1 and CB2 receptors. Work by a number of groups in recent years

September 19, 2019