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Research Library

Realm of Caring's Latest Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023

Recent studies have shown that even low amounts of D9-tetrahydrocannbinol (THC) within a cannabidiol (CBD) product can result in positive 11-nor-9-carboxy-D9- tetrahydrocannabinol (THC-COOH; a metabolite of THC) urine drug screens.

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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022

Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis users.   Methods: An anonymous online survey collected demographics, health information, and open-ended responses from medicinal cannabis users regarding perceptions, motivations,

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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021

Background: Anxiety and depressive disorders are highly prevalent. Patients are increasingly using medicinal cannabis products to treat these disorders, but little is known about the effects of medicinal cannabis use on

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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021

Abstract:    Recent approval of Epidiolex (pharmaceutical cannabidiol/CBD) for the treatment of Lennox Gastaut syndrome (LGS) and Dravet syndrome highlights a therapeutic efficacy of CBD in the treatment of epilepsy.

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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020

Introduction. Despite widespread legalization, the impact of medicinal cannabis use on patient level health and quality of life has not been carefully evaluated. The objective of this study was to

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Down and High: Reflections Regarding Depression and Cannabis


Abstract In light of the recent changes in the legal status of cannabis in Canada, the understanding of the potential impact of the use of cannabis by individuals suffering from […]

May 11, 2025


Sociodemographic Characteristics Associated With and Prevalence and Frequency of Cannabis Use Among Adults in the US


Abstract Importance  Cannabis use has increased, but there are few studies on frequent and daily cannabis use among US adults. Individuals who engage in higher frequency use may suffer more health […]


Cannabis: An Emerging Treatment for Common Symptoms in Older Adults


Please use this link to access this publication. Abstract BACKGROUND/OBJECTIVES Use of cannabis is increasing in a variety of populations in the United States; however, few investigations about how and […]

May 10, 2025


Cannabis Policy in the United States: Implications for Public Health


Abstract Introduction As of January 2021, a total of 36 states and the District of Columbia (DC) have legalized medical cannabis use, and 14 states and DC have legalized adult […]


Cannabis-Based Medicines and Medical Cannabis in the Treatment of Nociplastic Pain


Please use this link to access this publication. Abstract Nociplastic pain is defined as pain due to sensitization of the nervous system, without a sufficient underlying anatomical abnormality to explain […]


The antimicrobial effect behind Cannabis sativa


Abstract The development of multidrug-resistant bacteria has revealed the need for new antimicrobial compounds. Cannabis sativa preparations have a long history of medical applications, including the treatment of infectious diseases. This review […]


Exploring New Use of Cannabis among Older Adults


Please use this link to access this publication. ABSTRACT Objectives: In Canada, cannabis prohibition ended in October 2018. Older adults are the fastest growing group of cannabis users and are […]


Cannabis and driving ability


Please use this link to access this publication. Abstract The aim of this review is to discuss recent evidence on cannabis and driving ability. In particular, the review examines experimental […]


Medical cannabis and driving


Please use this link to access this publication. Abstract Background: Medical cannabis use is increasingly common in Australia. Patients and physicians need to be aware of the important implications that […]


Cannabis Marketing and Problematic Cannabis Use Among Adolescents


Please use this link to access this publication. Abstract Objective: Health consequences of commercializing nonmedical cannabis remain unclear, but data suggest that youth may encounter unintended risks. This study examined […]


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