Opioid-sparing effects of medical cannabis or cannabinoids for chronic pain: a systematic review and meta-analysis of randomised and observational studies

Please use this link to access this publication. Abstract Objective: To assess the efficacy and harms of adding medical cannabis to prescription opioids among people

March 25, 2024

Opioid-Sparing Effect of Cannabinoids: A Systematic Review and Meta-Analysis

Cannabinoids, when co-administered with opioids, may enable reduced opioid doses without loss of analgesic efficacy (ie, an opioidsparing effect). The aim of this study was

August 16, 2022

Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies

Abstract Cannabinoid co-administration may enable reduced opioid doses for analgesia. This updated systematic review on the opioid-sparing effects of cannabinoids considered preclinical and clinical studies

January 11, 2024

Opioid-enhancing antinociceptive effects of delta-9-tetrahydrocannabinol and amitriptyline in rhesus macaques

Please use this link to access this publication. Abstract Cannabinoids can enhance the antinociceptive effects of opioids in a synergistic manner, potentially reducing the analgesic

July 2, 2024

Opioid use in medical cannabis authorization adult patients from 2013 to 2018: Alberta, Canada

Abstract Background The opioid overdose epidemic in Canada and the United States has become a public health crisis – with exponential increases in opioid-related morbidity

June 28, 2025

Open Access Improving the regulation of medical cannabis in Canada to better serve pediatric patients

October 12, 2025

Open Access Attitudes toward medical cannabis among family physicians practising in Ontario, Canada: a qualitative research study

Abstract Background: Medical cannabis has been legally available in Canada since 2001, but its benefits and harms remain uncertain. We explored attitudes toward medical cannabis among

September 6, 2025

Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis users.   Methods: An anonymous online survey collected demographics, health information, and open-ended responses from medicinal

September 6, 2022

One-Stop Microfluidic Assembly of Human Brain Organoids To Model Prenatal Cannabis Exposure

Please use this link to access this publication. Abstract Prenatal cannabis exposure (PCE) influences human brain development, but it is challenging to model PCE using

July 2, 2024

On the impact of cannabis consumption on traffic safety: a driving simulator study with habitual cannabis consumers

Please use this link to access this publication. Abstract To contribute to the ongoing discussion about threshold limits of Δ9-tetrahydrocannabinol (THC) in road traffic, a

August 1, 2024