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Research Library

Realm of Caring's Latest Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023

Recent studies have shown that even low amounts of D9-tetrahydrocannbinol (THC) within a cannabidiol (CBD) product can result in positive 11-nor-9-carboxy-D9- tetrahydrocannabinol (THC-COOH; a metabolite of THC) urine drug screens.

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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022

Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis users.   Methods: An anonymous online survey collected demographics, health information, and open-ended responses from medicinal cannabis users regarding perceptions, motivations,

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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021

Background: Anxiety and depressive disorders are highly prevalent. Patients are increasingly using medicinal cannabis products to treat these disorders, but little is known about the effects of medicinal cannabis use on

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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021

Abstract:    Recent approval of Epidiolex (pharmaceutical cannabidiol/CBD) for the treatment of Lennox Gastaut syndrome (LGS) and Dravet syndrome highlights a therapeutic efficacy of CBD in the treatment of epilepsy.

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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020

Introduction. Despite widespread legalization, the impact of medicinal cannabis use on patient level health and quality of life has not been carefully evaluated. The objective of this study was to

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CANNUSE, a database of traditional Cannabis uses—an opportunity for new research


Abstract Cannabis is one of the most versatile genera in terms of plant uses and has been exploited by humans for millennia due to its medicinal properties, strong fibres, nutritious seeds […]

May 17, 2025


Quarterly trends in past-month cannabis use in the United States, 2015-2019


Please use this link to access this publication. Abstract Background Prevalence of cannabis use has been increasing among select subgroups in the US; however, trend analyses typically examine prevalence of […]


The association of type of cannabis product used and frequency of use with problematic cannabis use in a sample of young adult cannabis users


Please use this link to access this publication. Abstract Research exploring patterns and predictors of problematic cannabis use behaviors among young adults is limited. This knowledge is essential for intervening to prevent […]


Cannabis Policy Changes and Adolescent Cannabis Use: Evidence from Europe


Abstract Cannabis accounts for the largest share of the illicit drug market, with a high prevalence of use even among adolescents. To tackle this longstanding problem, many kinds of reforms […]


Cannabis and Inflammatory Mediators


Please use this link to access this publication. Abstract Introduction: Although the recreational cannabis use is expressive worldwide, the literature about medical potential of cannabis extracts, including its anti-inflammatory properties, remains […]


Cannabis use disorder and the lungs


Please use this link to access this publication. Abstract Cannabis is one of the world’s most widely used recreational drugs and the second most commonly smoked substance. Research on cannabis […]


Association of Cannabis Use During Adolescence With Neurodevelopment


Abstract Importance  Animal studies have shown that the adolescent brain is sensitive to disruptions in endocannabinoid signaling, resulting in altered neurodevelopment and lasting behavioral effects. However, few studies have investigated ties […]


Reasons for cannabis use during pregnancy and lactation: a qualitative study


Abstract Background: Cannabis use among pregnant and lactating people is increasing, despite clinical evidence showing that cannabis use may be associated with low birth weight and childhood developmental deficits. Our objective […]


Pharmacological properties, therapeutic potential, and legal status of Cannabis sativa L.: An overview


Please use this link to access this publication. Abstract Marijuana, or Cannabis sativa L., is a common psychoactive plant used for both recreational and medicinal purposes. In many countries, cannabis-based medicines have […]


Current controversies in medical cannabis: Recent developments in human clinical applications and potential therapeutics


Please use this link to access this publication. Abstract Knowledge about the therapeutic potential of medical cannabis has greatly improved over the past decade, with an ever-increasing range of developments in human […]


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