As more and more people are becoming interested in chronic disease management with cannabis, it is important to consider all aspects of chronic disease such as kidney diseases. This review discusses several articles that go over the efficacy and evidence in using cannabinoids to treat many of the symptoms that occur because of chronic kidney disease which could be used for healthcare practitioners to better formulate treatment plans for their patients. Abstract: Purpose of Review: Physical and psychological symptom burden in patients with advanced chronic kidney disease (CKD) is significantly debilitating; yet, it is often inadequately treated. Legalization of cannabis in Canada may...