Please use this link to access this publication. Abstract Background Driving under the influence of cannabis (DUIC) poses a significant public health threat. This study explores DUIC through a multifaceted lens, examining correlates of various wait times between cannabis use and driving, subjective perceptions of impairment, and differences between medical and non-medical cannabis users. Method Cross-sectional data from 979 cannabis users in Israel were collected through an online survey. DUIC risk was measured using reported wait times (categorized as low, moderate, and high risk) and driving while feeling cannabis effects. Logistic and multinomial regression identified correlates of DUIC risk. Results 23 % of the...

Please use this link to access this publication. Abstract Purpose of Review Sleep impairment due to chronic pain is linked to functional impairment and often inadequately addressed with current treatments leading some to seek alternative therapies, including cannabis. The factors associated with chronic pain and sleep impairments are disproportionately experienced by individuals from racial/ethnic minorities, of low socioeconomic status, who live in noisy, chaotic neighborhoods, and who have poor health care access. Recent Findings First, we describe the limited evidence for cannabis to manage pain and pain-related sleep impairment. Second, we highlight how research might exacerbate health inequities due to systematic biases in the...

Abstract Background: The trends of recreational use of cannabis and the use of cannabis for medical indications (i.e., “medical cannabis”) have grown in recent years. Despite that, there is still limited scientific evidence to guide clinical decision-making, and the strength of evidence for the medical use of cannabis is currently considered to be low. In contrast, there is growing evidence of negative health outcomes related to the use of cannabis. In this rapidly shifting landscape, the role of physician attitudes regarding the therapeutic value of cannabis has become essential. This study aimed to characterize knowledge/experience, attitudes, and potential predictors of clinical practice regarding medical cannabis....

Please use this link to access this publication. Abstract In recent years there has been an increase in cannabis use among adults in the U.S., which corresponds with changes in state-level laws making cannabis available for medical/recreational use. While cannabis became available for medical use in Florida in 2014, it was not until a ban on smoking cannabis was lifted in 2019 that the number of patients began to increase. The data for the current study are the Florida Young Adult Cannabis Study and focus on 415 medical cannabis patients (MCP). We identified several significant differences between male and female MCP. Female MCP initiated...

Please use this link to access this publication. Abstract Background Medical cannabis (MC) has gained traction in oncology for managing cancer-related symptoms, but its integration faces challenges due to limited evidence, inconsistent guidelines, and varied legal frameworks. Methods The TASMAN study aimed to assess the knowledge, attitudes, and practices of oncologists and palliative care providers globally regarding MC use in cancer care. A survey of healthcare providers from diverse regions and income levels was conducted. Results we study included 179 participants (response rate: 51.1 %), with an equal gender distribution (49.4 % female) and a median age of 37 years. Participants were primarily oncologists (71.5 %), practicing...

Please use this link to access this publication. Abstract Many people living with HIV (PLWH) use cannabis to manage symptoms, but a large proportion do so without medical cannabis authorization and use cannabis obtained outside the medical stream. In jurisdictions where non-medical cannabis use is legal, PLWH who hold medical cannabis authorization may represent a unique subgroup; yet, research on the correlates of using medical cannabis (authorized by a healthcare provider) in the context of non-medical cannabis legalization is lacking. Thus, this study examined the cannabis- and health-related correlates of medical cannabis use among PLWH in Ontario, Canada, where non-medical cannabis is legal. PLWH...

Abstract Introduction: Diabetic peripheral neuropathy (DPN) represents a prevalent neurological complication affecting millions of patients globally. This clinical investigation evaluated the therapeutic efficacy and safety profile of a novel transdermal medical cannabis formulation (THC:CBD:CBN) in treating painful DPN of the lower extremities. Methods: This phase III, double-blind, placebo-controlled, randomized clinical trial was conducted at Don Chan Hospital, Thailand, enrolling 100 participants over a 12-week intervention period. Using a computer-generated randomization sequence, participants were allocated to receive either the standardized cannabis formulation or a matched placebo. The primary outcome measure comprised pain intensity assessment using the validated Thai version of the Neuropathic Pain Symptom Inventory (NPSI-T). Secondary outcomes...

Abstract Background Canadian Veterans experiencing chronic pain report concerns about accessing accurate information on the risks associated with medical cannabis (MC) use. The Lower Risk Cannabis Use Guidelines (LRCUG) were developed to equip individuals who use cannabis recreationally with safer-use strategies. Many of the harm reduction recommendations for recreational cannabis use are relevant and important considerations for MC use. The primary objective of our study was to assess Canadian Veterans’ awareness of and interest in the LRCUG, and engagement in potential higher-risk MC use behaviours. Methods Canadian Armed Forces Veterans living with chronic pain (N = 582) were recruited online and through the Chronic Pain Centre...

Please use this link to access this publication. ABSTRACT This mixed-methods study investigated the role of medicinal cannabis use among younger adults who live in rural communities and experience high levels of cumulative social disadvantage (CSD). Results are based on cross-sectional surveys and online interviews with 153 younger adults (18–35-years old) in rural California. We assessed participants’ levels of CSD (high, medium, and low) and examined associations with perceived general physical and mental health and with medicinal use of cannabis (MUC). Qualitative analyses were then conducted to better understand the roles of cannabis use in the lives of study participants with high versus low...

Please use this link to access this publication. Abstract This study aimed to identify the strategies that medicinal cannabis patients employ to manage the risk of impaired driving, and the aetiological factors that influence the use of these strategies. A sample of medicinal cannabis patients (N = 58) from Queensland, Australia, participated in qualitative interviews. Thematic analysis revealed that medicinal cannabis patients employ a variety of strategies to mitigate impaired driving risk, despite commonly reporting driving after the recent use of cannabis. These strategies included the subjective assessment of impairment, waiting a specific post-consumption time-period, regulating cannabis consumption and driving behaviour, and adjusting on-road driving behaviour....