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Search Results for: thc pain – Page 5

Validation of a novel LC–MS-MS method for the separation and differentiation of Δ8- and Δ9-tetrahydrocannabinol isomers and their major metabolites in antemortem whole blood

…∆8-THC. Unfortunately, depending on the method of conversion, the amount of ∆8-THC, ∆9-THC, and other by-products can vary widely. For many laboratories, the emergence of ∆8-THC products resulted in analytical…

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April 12, 2026 No Comments
Blog

How Cannabis May Enhance Female Arousal and Orgasm

…make sex more pleasurable, this article will shed light on the potential benefits of THC for female sexual satisfaction.   Understanding THC and the Female Sexual Response   THC, or…

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October 8, 2024 No Comments
Blog

Cannabinoids for the Symptoms of Autism: A Review of the Science

…propensity to develop schizophrenic symptoms? Answer: Medical cannabis use and recreational THC use are not comparable. Clinically supervised regimens rarely involve high-dose THC alone, as this can lead to tolerance…

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November 12, 2025 No Comments

Effectiveness and tolerability of THC:CBD oromucosal spray as add-on measure in patients with severe chronic pain: analysis of 12-week open-label real-world data provided by the German Pain e-Registry

…74.1%), least with neuropathic pain (n=1, 0.2%; p<0.001). Conclusion: THC:CBD oromucosal spray proved to be an effective and well-tolerated add-on treatment for patients with elsewhere refractory chronic pain – especially…

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August 1, 2024 No Comments

Medical Cannabis for Gynecologic Pain Conditions

…for gynecologic pain and its effectiveness as an analgesic. DATA SOURCES: We searched PubMed, EMBASE, Scopus, Cochrane, and ClinicalTrials.gov using terms for “woman,” “cannabis,” and “pain” or “pelvic pain” or…

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February 28, 2024 No Comments

Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats

…CBD/THC but not those given THC alone. With both acute and chronic administration, CBD pre-treatment potentiated blood and brain THC levels, and lowered levels of THC metabolites (THC-COOH and 11-OH-THC)….

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September 4, 2024 No Comments

Behavioral Battery for Testing Candidate Analgesics in Mice. II. Effects of Endocannabinoid Catabolic Enzyme Inhibitors and ∆9-Tetrahydrocannabinol

…candidate analgesics. This study compared effects of MAGL and FAAH inhibitors with effects of ∆9-tetrahydrocannabinol (THC) using a battery of pain-stimulated, pain-depressed, and pain-independent behaviors in male and female mice….

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May 20, 2024 No Comments

Cannabinoids in Chronic Non-Cancer Pain: A Systematic Review and Meta-Analysis

Abstract Background: For patients with chronic, non-cancer pain, traditional pain-relieving medications include opioids, which have shown benefits but are associated with increased risks of addiction and adverse effects. Medical cannabis…

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September 13, 2025 No Comments

Cannabidiol-Δ9-tetrahydrocannabinol interactions on acute pain and locomotor activity

…locomotor activity at 6 h post-injection, but enhanced THC-induced hypolocomotion 4–6 h post-THC injection, at lower THC doses. There were no sex differences in CBD-THC interactions. In Experiments 2 and…

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September 4, 2024 No Comments

Effect of Cannabidiol and Δ9-Tetrahydrocannabinol on Driving Performance

…(N = 26) were healthy occasional users of cannabis. Interventions Participants vaporized THC-dominant, CBD-dominant, THC/CBD-equivalent, and placebo cannabis. THC and CBD doses were 13.75 mg. Order of conditions was randomized…

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May 31, 2024 No Comments
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