…was weak in modulation of experimental pain. Imipramine attenuated pain in most experimental models, whereas amitriptyline had weaker effects. Delta-9-tetrahydrocannabinol attenuated pain in only a few models. CONCLUSIONS Pain induction…
…CBD on controlling cancer pain, which have been reviewed and summarised. Five studies that evaluated THC oil capsules, THC:CBD oromucosal spray (nabiximols), or THC oromucosal sprays found some evidence of…
…make sex more pleasurable, this article will shed light on the potential benefits of THC for female sexual satisfaction. Understanding THC and the Female Sexual Response THC, or…
…propensity to develop schizophrenic symptoms? Answer: Medical cannabis use and recreational THC use are not comparable. Clinically supervised regimens rarely involve high-dose THC alone, as this can lead to tolerance…
…placebo (control intervention) in patients with acute, chronic non-malignant, or cancer pain. Outcomes examined were pain intensity scores, pain relief scores, and adverse effects. Validity of trials was assessed independently…
…and key secondary objectives were pain interference and quality of life. Pain intensity was measured using the Numeric Rating Scale (NRS) of the Brief Pain Inventory (BPI) questionnaire. Pain interference…
…used to analyze data from 131,582 sessions in which inhaled cannabis was used to treat “muscle pain,” “joint pain,” or “nerve pain.” Results: For all three pain symptoms, severity ratings…
…CBD/THC but not those given THC alone. With both acute and chronic administration, CBD pre-treatment potentiated blood and brain THC levels, and lowered levels of THC metabolites (THC-COOH and 11-OH-THC)….
…locomotor activity at 6 h post-injection, but enhanced THC-induced hypolocomotion 4–6 h post-THC injection, at lower THC doses. There were no sex differences in CBD-THC interactions. In Experiments 2 and…
…(N = 26) were healthy occasional users of cannabis. Interventions Participants vaporized THC-dominant, CBD-dominant, THC/CBD-equivalent, and placebo cannabis. THC and CBD doses were 13.75 mg. Order of conditions was randomized…
