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Featured Articles: Realm of Caring's Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023
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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022
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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021
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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021
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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020
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Pharmacodynamic dose effects of oral cannabis ingestion in healthy adults who infrequently use cannabis


Please use this link to access this publication. Abstract Background Prior controlled cannabis research has mostly focused on smoked cannabis and predominantly included frequent cannabis

July 1, 2024


Persistent sexually dimorphic effects of adolescent THC exposure on hippocampal synaptic plasticity and episodic memory in rodents


ABSTRACT There is evidence that cannabis use during adolescence leads to memory and cognitive problems in young adulthood but little is known about effects of

February 12, 2024


Persistent Exposure to Δ9-Tetrahydrocannabinol during Adolescence Does Not Affect Nociceptive Responding in Adult Mice


Abstract Evidence suggests that Δ9-tetrahydrocannabinol (Δ9-THC), the intoxicating component of cannabis, causes enduring changes in the structure and function of adolescent brain circuits implicated in

May 20, 2024


Peripheral Endogenous Cannabinoid Levels Are Increased in Schizophrenia Patients Evaluated in a Psychiatric Emergency Setting


ABSTRACT Background: The endogenous cannabinoid system mediates the psychoactive effects of cannabis in the brain. It has been argued that this system may play a key

September 19, 2025


Peripheral cannabinoid receptor, CB2, regulates bone mass


The endogenous cannabinoids bind to and activate two G proteincoupled receptors, the predominantly central cannabinoid receptor type 1 (CB1) and peripheral cannabinoid receptor type 2

September 19, 2019


Perioperative Pain and Addiction Interdisciplinary Network (PAIN): consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users by a modified Delphi process


Abstract Summary In many countries, liberalisation of the legislation regulating the use of cannabis has outpaced rigorous scientific studies, and a growing number of patients

July 20, 2025


Perioperative cannabis use: a longitudinal study of associated clinical characteristics and surgical outcomes


Please use this link to access this publication. Abstract Background Despite increases in cannabis use generally and for pain management, data regarding cannabis use in patients

October 11, 2025


Perioperative Cannabis as a Potential Solution for Reducing Opioid and Benzodiazepine Dependence


Please use this link to access this publication. Abstract Importance  Cannabis is increasingly being used for medicinal purposes but remains outside Western medical practice. Data on

July 5, 2025


Perinatal CBD or THC Exposure Results in Lasting Resistance to Fluoxetine in the Forced Swim Test: Reversal by Fatty Acid Amide Hydrolase Inhibition


Abstract Introduction: There is widespread acceptance of cannabis for medical or recreational use across the society, including pregnant women. Concerningly, numerous studies find that the developing

January 15, 2024


Perceptions, Experiences, and Patterns of Cannabis Use in Individuals with Mood and Anxiety Disorders in the Context of Cannabis Legalization and Medical Cannabis Program in Canada – A Qualitative Study


Abstract Introduction Perceptions of cannabis as a potential medical treatment for mood and anxiety disorders have been increasing in the context of legalizations, availability, and medical

October 30, 2024


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