Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation

Background: Endocannabinoids are among the most intensively studied lipid mediators of cardiovascular functions. In the present study the effects of decreased and increased activity of

September 19, 2019

Role of CB2 receptors in social and aggressive behavior in male mice

Rationale Male CB1KO mice exhibit stronger aggressive responses than wild-type mice. Objective This study was designed to examine the role of cannabinoid CB2r in social

Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review

Abstract Chronic non-cancer pain, defined by the Center for Disease Control and Prevention (CDC) as lasting beyond three months, significantly affects individuals’ quality of life

December 7, 2025

Role of cannabis in inflammatory bowel diseases

Abstract For many centuries, cannabis (marijuana) has been used for both recreational and medicinal purposes. Currently, there are about 192 million cannabis users worldwide, constituting

July 2, 2024

Role of cannabis in cardiovascular disorders

Abstract The growing popularity of medical and recreational consumption of cannabis, especially among the youth, raises immediate concerns regarding its safety and long-terms effects. The

October 30, 2024

Role of cannabinoids in the regulation of bone remodeling

The endocannabinoid system plays a key role in regulating a variety of physiological processes such as appetite control and energy balance, pain perception, and immune

September 19, 2019

Role of cannabinoids in pain management

Cannabinoids are pharmacological agents of endogenous (endocannabinoids), botanical (phytocannabinoids), or synthetic origin; Cannabinoids alleviate pain through a variety ofreceptor and non-receptor mechanisms including direct analgesic

Role of Cannabinoids in Gastrointestinal Mucosal Defense and Inflammation

Modulating the activity of the endocannabinoid system influences various gastrointestinal physiological and pathophysiological processes, and cannabinoid receptors as well as regulatory enzymes responsible for the

September 16, 2020

Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders

Abstract Drug treatments available for the management of substance use disorders (SUD) present multiple limitations in efficacy, lack of approved treatments or alarming relapse rates.

April 16, 2024

Role of Cannabidiol for Improvement of the Quality of Life in Cancer Patients: Potential and Challenges

Abstract There is currently a growing interest in the use of cannabidiol (CBD) to alleviate the symptoms caused by cancer, including pain, sleep disruption, and

January 18, 2024