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Featured Articles: Realm of Caring's Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023
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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022
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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021
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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021
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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020
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Role of Cannabidiol and Tetrahydrocannabivarin on Paclitaxel-induced neuropathic pain in rodents


Please use this link to access this publication Abstract The purpose of this study was to evaluate if phytocannabinoids, synthetic cannabidiol (CBD), and tetrahydrocannabivarin (THCV),

January 31, 2024


Role of 5HT1A Receptors in the Neuroprotective and Behavioral Effects of Cannabidiol in Hypoxic–Ischemic Newborn Piglets


Abstract Background: Hypoxic–ischemic (HI) insults have important deleterious consequences in newborns, including short-term morbidity with neuromotor and cognitive disturbances. Cannabidiol (CBD) has demonstrated robust neuroprotective

January 30, 2024


Risk-thresholds for the association between frequency of cannabis use and the development of psychosis: a systematic review and meta-analysis


Abstract BackgroundEpidemiological studies show a dose–response association between cannabis use and the risk of psychosis. This review aimed to determine whether there are identifiable risk-thresholds

February 29, 2024


Risk thresholds for the frequency of cannabis use during pregnancy and adverse neonatal outcomes: protocol for a systematic review and dose-response meta-analysis


Abstract Background Cannabis use during pregnancy has been increasing and is associated with adverse neonatal outcomes, such as low birth weight (LBW) and preterm birth (PTB).

December 7, 2025


Risk Factors for Cannabis-Related Mental Health Harms in Older Adults: A Review


Please use this link to access this publication. ABSTRACT Objectives: This paper reviews research on the topic of cannabis use and mental health harms in older

October 13, 2025


Review on clinical studies with cannabis and cannabinoids 2010-2014


In 2010 a review by Hazekamp and Grotenhermen covered controlled clinical trials of the years 2006-2009 on cannabis-based medicines, which followed the example of the

September 19, 2019


Review of the Use of Medicinal Cannabis Products in Palliative Care


Simple Summary Symptom management is a key goal of palliative cancer care. There is growing interest in the use of cannabis-based medicines or products for

December 2, 2024


Review of the neurological benefits of phytocannabinoids


Background: Numerous physical, psychological, and emotional benefits have been attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia. The

September 16, 2020


Review of the Endocannabinoid System


Please use this link to access this publication. Abstract The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in the developing central nervous system

April 19, 2024


Review of cannabis use and propofol anesthesia: recent insights and clinical implications


Please use this link to access this publication. Abstract Purpose of review We examine recent evidence and clinical implications of pharmacological interactions between cannabis and

November 20, 2025


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