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Featured Articles: Realm of Caring's Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023
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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022
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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021
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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021
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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020
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The association between cannabis use and testicular function in men: A systematic review and meta-analysis


Abstract   Objective To evaluate the association between cannabis use and testicular function (as assessed through semen quality and serum hormone levels) in different populations.

August 24, 2023


The association between cannabis use and paranoia: Meta-analysis of experimental and observational studies


Abstract Paranoia is common and has negative implications at clinical and societal levels. Cannabis may cause paranoia, although conflicting evidence exists. We reviewed studies on

December 21, 2025


The association between cannabis use and outcome in pharmacological treatment for opioid use disorder


Abstract Background With the ongoing opioid crisis and policy changes regarding legalization of cannabis occurring around the world, it is necessary to consider cannabis use

June 13, 2025


The association between cannabis use and depression: a systematic review and meta-analysis of longitudinal studies


Please use this link to access this publication: https://www.cambridge.org/core/journals/psychological-medicine/article/abs/association-between-cannabis-use-and-depression-a-systematic-review-and-metaanalysis-of-longitudinal-studies/B144B7AE5A3D973289DBDD99ADE21E58 Abstract BackgroundLongitudinal studies reporting the association between cannabis use and developing depression provide mixed results. The objective

November 15, 2023


The association between cannabis use and anxiety disorders: Results from a population-based representative sample


Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0924977X15004204?via%3Dihub Abstract The cross-sectional association between cannabis use and anxiety disorders is well documented, yet less is known


The association between cannabis and depression: an updated Systematic Review and Meta-analysis


Abstract BackgroundCannabis is one of the most commonly used drugs globally, although its legal status varies across regions. Public support for its decriminalization has increased,

November 22, 2025


The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors


Please use this link to access this publication: https://link.springer.com/article/10.1007/s00213-010-2036-z Abstract Rationale: Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that induces anxiolytic-like effects in rodents and

November 15, 2023


The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system


Cannabidiol (CBD), the main non-psychotomimetic component of the plant Cannabis sativa, exerts therapeutically promising effects on human mental health such as inhibition of psychosis, anxiety

September 19, 2019


The anxiolytic effect of cannabidiol depends on the nature of the trauma when patients with post-traumatic stress disorder recall their trigger event


Abstract Objectives: We assessed whether administering cannabidiol (CBD) before recalling the traumatic event that triggered their disorder attenuates anxiety in patients with post-traumatic stress disorder

January 31, 2024


The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids


As a therapeutic agent, most people are familiar with the palliative effects of the primary psychoactive constituent of Cannabis sativa (CS), Δ9 -tetrahydrocannabinol (THC), a

September 19, 2019


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