The endocannabinoid 2-AG protects the blood–brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines

Endocannabinoids are involved in neuroprotection through numerous biochemical pathways. We have shown that the endocannabinoid 2- arachidonoyl glycerol (2-AG) is released in mouse brain after

September 19, 2019

The Emerging Role of the Endocannabinoid System in the Sleep-Wake Cycle Modulation

The endocannabinoid system comprises amides, esters and ethers of long chain polyunsaturated fatty acids. Narachidonoylethanolamide (anandamide; ANA) and 2-arachidonoylglycerol (2-AG) are endogenous cannabinoids (endocannabinoids) ligands

The Emerging Role of the Endocannabinoid System in Endocrine Regulation and Energy Balance

During the last few years, the endocannabinoid system has emerged as a highly relevant topic in the scientific community. Many different regulatory actions have been

The electrophysiological effects of cannabidiol on action potentials and transmembrane potassium currents in rabbit and dog cardiac ventricular preparations

Abstract Cannabis use is associated with known cardiovascular side effects such as cardiac arrhythmias or even sudden cardiac death. The mechanisms behind these adverse effects

April 23, 2024

The electrophysiological effect of cannabidiol on hERG current and in guinea-pig and rabbit cardiac preparations

Abstract Interest is increasing regarding use of Cannabidiol (CBD) in companion animals due to anecdotal evidence of beneficial behavioral and health effects. The purpose of

July 1, 2024

The Efficacy of Medical Marijuana in the Treatment of Cancer-Related Pain

Please use this link to access this publication. Abstract Background: The opioid epidemic has spurred investigations for nonopioid options, yet limited research persists on medical marijuana’s

July 2, 2024

The Efficacy of Cannabis on Multiple Sclerosis-Related Symptoms

Abstract Multiple sclerosis (MS) is known as an autoimmune disease that damages the neurons in the central nervous system. MS is characterized by its most

February 29, 2024

The Efficacy of Cannabis in Oncology Patient Care and Its Anti-Tumor Effects

Simple Summary Cancer is a major disease and a leading cause of death worldwide. Improving treatment and management strategies for cancer is critical. This article

December 17, 2024

The efficacy and safety of cannabidiol as adjunct treatment for drug-resistant idiopathic epilepsy in 51 dogs: A double-blinded crossover study

Abstract Background Approximately 30% of dogs with idiopathic epilepsy (IE) are drug-resistant. Recent studies have suggested cannabidiol (CBD) may be an effective anticonvulsant in dogs

January 11, 2024

The effects of Δ9-tetrahydrocannabinol on the dopamine system

Please use this link to access this publication. Abstract The effects of Δ9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, are a pressing concern for

September 4, 2024