Abstract Introduction: Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions that impact behavior, communication, social interaction, and learning abilities. Treatment of ASD with medical cannabis (MC) shows promising results in reducing the severity of certain behavioral aspects. The goals of this observational study are to demonstrate the potential of metabolic biomarkers to (1) objectively determine the impact on metabolites of MC treatment and (2) suggest the metabolic pathways of children with ASD, who respond to MC treatment. Materials and Methods: The impact of effective physician-supervised MC treatment on children with ASD (n=15), compared with an age-matched group of typically developing (TD; n=9) children, was evaluated...

Please use this link to access this publication: https://psycnet.apa.org/record/2023-16721-001 Abstract Objective: We examined the extent to which behavioral ratings of children’s executive function (EF) in early adolescence predicted adolescents’ cannabis use, and whether associations were independent of parents’ cannabis and alcohol use and adolescents’ alcohol use. Method: Participants were 198 offspring (44% boys) of 127 mothers and 106 fathers. Parents and teachers completed the Behavior Rating Inventory of Executive Function (BRIEF) at ages 11–14 years. Youth were interviewed repeatedly from ages 14 to 20 years regarding frequency of cannabis and alcohol use. Two-level models regressed dichotomous cannabis outcomes (annual, weekly, or daily use) on age...

Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0024320523004733 Abstract There has been an increased interest of the scientific community in cannabis and its constituents for therapeutic purposes. Although it is believed that cannabinoids can be effective for a few different conditions and syndromes, there are little objective data that clearly support the use of cannabis, cannabis extracts or even cannabidiol (CBD) oil. This review aims to explore the therapeutic potential of phytocannabinoids and synthetic cannabinoids for the treatment of several diseases. A broad search covering the past five years, was performed in PubMed and ClinicalTrial.gov databases, to identify papers focusing on the use of medical phytocannabinoids in terms of tolerability, efficacy and safety....

Please use this link to access this publication: https://psycnet.apa.org/record/2022-00077-001 Abstract While previous research has indicated that alcohol use is associated with difficulties in emotion processing and socioemotional functioning, less is known about the effects of cannabis on these functions. The purpose of this review article is to provide the current state of knowledge on the effects of cannabis on emotion processing with regard to behavioral, physiological, and neural responses. This narrative review synthesizes previous research investigating the effects of cannabis on emotion processing across studies that have utilized a number of experimental approaches to determine both the acute and chronic effects of cannabis on emotion...

Abstract The majority of states have fully legalized the use of medical cannabis (MC), and nearly all other states allow limited access to cannabidiol (CBD), a non-intoxicating constituent of cannabis often touted for a range of therapeutic indications. Further, the Agricultural Improvement Act of 2018 legalized hemp-derived products in all 50 states; typically high in CBD, these products are derived from cannabis varieties containing ≤0.3% delta-9-tetrahydrocannabinol (THC) by weight. The recent “green rush” has resulted in a striking increase in cannabis use among patients and consumers who often use a wide variety of novel product types, each with a unique blend of cannabinoid constituents....

Please use this link to access this publication: https://journals.sagepub.com/doi/abs/10.1177/00914150221128971 Abstract Cannabis use is growing among older adults to manage medical concerns including poor sleep. In this study, we characterized how patients seen at a geriatrics clinic use cannabis to address sleep disturbance. Specifically, we conducted an anonymous survey of 568 adults, including 83 who reported cannabis use within the past 3 years, to inquire about such use. We compared cannabis use characteristics between those using it for sleep disturbance versus all other conditions. We considered a p-value <.10 to be statistically significant. Among the cannabis users in our sample, 29% reported using cannabis for sleep disturbance...

Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0889157522005804 Abstract Nowadays, hemp (Cannabis sativa) seeds are receiving increased attention because of their high nutritional value. Among other nutrients, they contain a PUFA- and bioactive compounds-rich oil. Accordingly, this work was focused to establish the fatty acids (FA) content, the regiospecificity of triacylglycerols, and to quantify several bioactive compounds of relevant hemp seeds varieties and related taxa. Eight varieties of unhusked hemp seeds and eight samples of commercial husked hemp seeds were studied, and other Cannabaceae seeds: those from hop (Humulus lupulus) and European hackberry (Celtis australis). We found that all hemp seeds varieties constitute a rich source of essential...

Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0378874123007079 Abstract Ethnopharmacological relevance Cannabis sativa L. (Cannabaceae) is a plant native to Eastern Asia spread throughout the world because of its medicinal properties. Despite being used for thousands of years as a palliative therapeutic agent for many pathologies, in many countries research on its effects and properties could only be carried out in recent years, after its legalization. Aims of the study Increasing resistance to traditional antimicrobial agents demands finding new strategies to fight against microbial infections in medical therapy and agricultural activities. Upon legalization in many countries, Cannabis sativa is gaining attention as a new source...

Abstract Cannabis sativa is a medicinal plant that has been known for years and is used as an Ayurvedic medicine. This plant has great potential in treating various types of brain diseases. Phytochemicals present in this plant act as antioxidants by maintaining synaptic plasticity and preventing neuronal loss. Cannabidiol (CBD) and Tetrahydrocannabinol (THC) are both beneficial in treating Alzheimer’s disease by increasing the solubility of Aβ42 amyloid and Tau aggregation. Apart from these therapeutic effects, there are certain unknown functions of these phytochemicals in Alzheimer’s disease that we want to elucidate through this study. In this research, our approach is to analyze the effect of...

Please use this link to access this publication: https://www.liebertpub.com/doi/full/10.1089/can.2021.0044 Abstract Background: The current social and legal landscape is likely to foster the medicinal and recreational use of cannabis. Synthetic cannabinoid use is associated with acute kidney injury (AKI) in case reports; however, the association between natural cannabis use and AKI risk in patients with advanced chronic kidney disease (CKD) is unknown. Materials and Methods: From a nationally representative cohort of 102,477 U.S. veterans transitioning to dialysis between 2007 and 2015, we identified 2215 patients with advanced CKD who had undergone urine toxicology (UTOX) tests within a year before dialysis initiation and had inpatient serial serum creatinine levels...