Abstract Introduction: An estimated 54 million Americans currently sufer from debilitating arthritis. Patients who have exhausted conservative measures can be subject to chronic pain and resort to symptomatic management with antiinfammatories, acetaminophen, and opioids. Cannabidiol (CBD) is a non-psychoactive cannabinoid that has shown promise in preclinical studies to reduce infammation and pain associated with arthritis. The purpose of this study was to explore patient perceived efects of cannabidiol on symptoms of arthritis. Methods: A novel anonymous questionnaire was created to evaluate perceived efcacy of cannabidiol for the treatment of arthritis. A self-selected convenience sample (N=428) was recruited through online methods including social media accounts...