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Research Library

Realm of Caring's Latest Published Research

Likelihood of Positive Urine Screens of THC-COOH After Daily Use of Full-Spectrum Hemp Extracts

January 23, 2023

Recent studies have shown that even low amounts of D9-tetrahydrocannbinol (THC) within a cannabidiol (CBD) product can result in positive 11-nor-9-carboxy-D9- tetrahydrocannabinol (THC-COOH; a metabolite of THC) urine drug screens.

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Online survey of medicinal cannabis users: Qualitative analysis of patient-level data

September 6, 2022

Aim: To characterize perceived benefits and challenges experienced by medicinal cannabis users.   Methods: An anonymous online survey collected demographics, health information, and open-ended responses from medicinal cannabis users regarding perceptions, motivations,

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Antidepressant and Anxiolytic Effects of Medicinal Cannabis Use in an Observational Trial

September 9, 2021

Background: Anxiety and depressive disorders are highly prevalent. Patients are increasingly using medicinal cannabis products to treat these disorders, but little is known about the effects of medicinal cannabis use on

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Cross-sectional and longitudinal evaluation of cannabidiol (CBD) product use and health among people with epilepsy

July 27, 2021

Abstract:    Recent approval of Epidiolex (pharmaceutical cannabidiol/CBD) for the treatment of Lennox Gastaut syndrome (LGS) and Dravet syndrome highlights a therapeutic efficacy of CBD in the treatment of epilepsy.

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A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health

May 19, 2020

Introduction. Despite widespread legalization, the impact of medicinal cannabis use on patient level health and quality of life has not been carefully evaluated. The objective of this study was to

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Evaluation of cannabis-derived anti-inflammatory and analgesic treatment in animals and identification of cannabinoid-based effective inhibition of prostaglandin through computational studies


Please use this link to access this publication. Abstract Many medical conditions are accompanied by severe pain. Acute pain refers to the experience of pain that lasts for only a […]

April 26, 2025


A National Survey Study of Cannabis Use During Menopause: Identifying Variables Associated With Recreational, Medical, and Hybrid Use


Please use this link to access this publication. Abstract Objective: Previous research has demonstrated different cannabis-related outcomes depending on the goal of cannabis use (i.e., recreational, medical, a hybrid of […]

April 25, 2025


Cannabis expectancies and associations with cannabis use and health functioning among adults with chronic pain


Please use this link to access this publication. Abstract Introduction Cannabis is increasingly available to individuals in the United States, with the majority of states legalizing medical or recreational cannabis […]

April 23, 2025


The acute effects of vaporized cannabis on drivers’ hazard perception and risk-taking behaviors in medicinal patients: A within-subjects experiment


Abstract Introduction: As the medically prescribed use of cannabis flower continues to increase, there is a need to understand how vaporized cannabis can acutely affect driving-related skills and risk-taking behaviors […]


Unmet Healthcare Needs and Medical Cannabis Use Among Sexual and Gender Minoritized Adults in a High-Stigma Environment


Please use this link to access this publication. ABSTRACT Sexual and gender minoritized (SGM) individuals in high-stigma areas may use cannabis to cope with unmet healthcare needs and elevated stress. […]


Haven’t I waited long enough? The role of wait times and subjective impairment in cannabis-related driving behavior


Please use this link to access this publication. Abstract Background Driving under the influence of cannabis (DUIC) poses a significant public health threat. This study explores DUIC through a multifaceted […]


The State of the Evidence for Medical Cannabis as a Treatment for Pain-related Sleep Impairments: Integrating Social Determinants of Health into Research Design and Policy


Please use this link to access this publication. Abstract Purpose of Review Sleep impairment due to chronic pain is linked to functional impairment and often inadequately addressed with current treatments […]


International perspectives on physician knowledge, attitudes, and practices related to medical cannabis


Abstract Background: The trends of recreational use of cannabis and the use of cannabis for medical indications (i.e., “medical cannabis”) have grown in recent years. Despite that, there is still limited […]


Young Adult Medical Cannabis Patients in Florida: Gender Differences in Characteristics of use, Experiences at Dispensaries, and Association With Health-Related Problems


Please use this link to access this publication. Abstract In recent years there has been an increase in cannabis use among adults in the U.S., which corresponds with changes in […]


An international survey on the knowledge, attitudes and clinical patterns of use of medical cannabis for cancer care: The TASMAN study


Please use this link to access this publication. Abstract Background Medical cannabis (MC) has gained traction in oncology for managing cancer-related symptoms, but its integration faces challenges due to limited […]


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