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  • ∆9-tetrahydrocannabinol (THC), Cannabis
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Knowledge and attitude of college students towards cannabis use in urban India: A comparative perspective of users and non-users

Abstract Background We aimed to assess the knowledge and attitude about cannabis use among college students in India, compare the perspective among users and non-users and lay a framework for development of effective primary prevention strategies in future. Methods This cross-sectional study was done in different colleges of Mumbai. Two hundred and sixty students of both sexes aged between 18 and 25 years were selected by systematic random sampling. Participants had to fill a sociodemographic questionnaire and a self-administered questionnaire that was analysed using the Statistical Package for the Social Sciences software. Results About 11.2% of the participants were users of cannabis and around...
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Sleep-Related Cannabis Expectancy Questionnaire (SR-CEQ): Factor Analysis Replication, Internal Reliability, and Construct Validity

Please use this link to access this publication. Abstract Expectancies regarding the sleep-promoting effects of cannabis may exacerbate the propensity to self-medicate sleep problems with cannabis. Given the potential clinical importance of expectancies for the sedative effects of cannabis, Goodhines et al (2020) developed the Sleep-Related Cannabis Expectancies Questionnaire (SR-CEQ). However, concurrent validity of this instrument has not been evaluated. This study aimed to replicate the two-factor structure and internal reliability and explore incremental construct validity of the SR-CEQ. Cross-sectional online survey data were collected from 287 college students (Mage = 19.07 ± 1.44 years, range 18-25; 47% male; 84% non-Hispanic White; 61% lifetime cannabis...
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Evidence on the effect of in-utero cannabis exposure in neonates

Please use this link to access this publication. Abstract The global prevalence of cannabis use during pregnancy is increasing, driven by perceived therapeutic benefits and greater societal acceptance. Concurrently, the psychoactive potency of cannabis products has risen significantly, due to increase in concentrations of Tetrahydrocannabinol (THC) from 5% to 30%. THC crosses the placenta, disrupts the endocannabinoid system critical for neurodevelopment, and accumulates in fetal tissues. THC is transferred into breast milk, with breastfed infants receiving ~2.5% of the maternal dose, raising concerns regarding neurodevelopmental consequences. An increasing number of studies and metanalysis have demonstrated association of prenatal cannabis exposure with low birth weight,...
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Review and Call for Improved Cannabis Measurement and the Potential for Leveraging Cannabis Seed-To-Sale Systems

Please use this link to access this publication. ABSTRACT International consensus has emerged, which proposes that the measurement and standardization of the quantity of THC potency, or dose (mgTHC), is a requisite for identifying consistent relationships between patterns of cannabis use and the risk for negative health outcomes, especially critical given the increasing number of U.S. states and European countries considering legalizing cannabis for recreational use. Despite the lack of measurement approaches that provide accurate, real-time data on THC dosage, the number of states that have implemented legal adult use cannabis markets has coincided with the use of regulatory seed-to-sale or track-and-trace systems. Seed-to-sale...
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Effects of Cannabis Use on Neurocognition: A Scoping Review of MRI Studies

Please use this link to access this publication. Abstract Cannabis is one of the most commonly utilized recreational drugs. However, increasing evidence from the literature suggests harmful implications on cognition. Thus, the main aim of the current review is to summarize literature findings pertaining to the impact of cannabis on neurocognitive skills, focusing on the imaging biomarkers provided by MRI. Two reviewers navigated the literature independently using four main search engines including PubMed and Cochrane. Articles were first evaluated through their title and abstract, followed by full-text assessment. Study characteristics and findings were extracted, and the studies' quality was appraised. 47 articles were included....
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Maternal Cannabis Use During Pregnancy and Neuropsychiatric Adverse Outcomes During Childhood and Early Adult Life

Abstract Cannabis use during pregnancy is increasing; the study of adverse outcomes in cannabis-exposed pregnancies is therefore important. Previous articles in this series described increased risks of maternal adverse outcomes, fetal adverse outcomes, birth defects in newborns, and autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) in childhood. This article examines neuropsychiatric adverse outcomes in offspring gestationally exposed to cannabis. Currently available research suggests that prenatal cannabis exposure is associated with increased risks of ASD, ADHD, psychosis proneness, psychotic like experiences, internalizing problems, externalizing problems, attention problems, thought-related problems, social problems, impaired executive function, and observed aggression. There is insufficient study of prenatal cannabis...
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Cannabis-Bacteria Interaction: Trends in Secondary Metabolites, Biocontrol, and By-products

Abstract In the last decade, the interest in cannabis cultivation has grown significantly, driven by its various applications and the presence of key cannabinoids such as cannabidiol (CBD) and cannabigerol (CBG). However, this increase in production has heightened susceptibility to contaminants, especially microorganisms, such as pathogenic bacteria, which pose risks to both human health and the plant itself. Nonetheless, a promising outlook emerges with the biological utilization of certain bacterial species. This study focused on a bibliometric evaluation of the interaction between Cannabis and bacteria, analyzing research trends related to metabolites, biocontrol, and by-products. To achieve this, scientific literature was reviewed in databases such...
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Medical Marijuana Documentation Practices in Patient Electronic Health Records: Retrospective Observational Study Using Smart Data Elements and a Review of Medical Records

Abstract Background: Medical marijuana (MMJ) is available in Pennsylvania, and participation in the state-regulated program requires patient registration and receiving certification by an approved physician. Currently, no integration of MMJ certification data with health records exists in Pennsylvania that would allow clinicians to rapidly identify patients using MMJ, as exists with other scheduled drugs. This absence of a formal data sharing structure necessitates tools aiding in consistent documentation practices to enable comprehensive patient care. Customized smart data elements (SDEs) were made available to clinicians at an integrated health system, Geisinger, following MMJ legalization in Pennsylvania. Objective: The purpose of this project was to examine and contextualize...
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Impact of Computer-Mediated Versus Face-to-Face Motivational-Type Interviews on Participants’ Language and Subsequent Cannabis Use: Randomized Controlled Trial

Abstract Background: Motivational interviewing (MI) is frequently used to facilitate behavior change. The use of change talk during motivational interviews can predict subsequent behavior change. However, no studies have compared the information obtained from traditional face-to-face motivational interviews and computer-mediated motivational interviews or resulted in the same amount of behavior change. Objective: This study aimed to investigate if face-to-face motivational-type interviews (MTIs) and computer-mediated MTIs elicit the same amount of "change talk" and behavior change when young adults discuss their ambivalence about using marijuana. Methods: A total of 150 users, including frequent marijuana users, occasional marijuana users, and non-marijuana users, participated in the study. All participants reported...
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The prevalence of tobacco, alcohol, stimulant, khat, and cannabis use among school-going students in African and Arab countries: a systematic review and meta-analysis

Abstract Objectives The objectives of this review and meta-analysis were twofold: first, to determine the prevalence of substance use among school-going children in Arab and African countries; and second, to highlight the considerable influence of variables such as the nation’s region and the timeframe of the study on the prevalence of substance use. Methods Research was sourced from Science Direct, Scopus, Web of Science, Google Scholar, and PubMed. Thirty-seven articles were incorporated in accordance with the PRISMA guidelines. This review included studies published from 2013 to 2023. The statistical meta-analysis was performed using Comprehensive Meta-Analysis ver. 3 software. Across 37 studies, the total number...
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