Please use this link to access this publication. Highlights • Medical Marijuana use is correlated with control of pain, anxiety, and poor appetite in ALS patients. • Medical Marijuana use is not correlated with control of insomnia or spasticity in ALS patients. • Medical Marijuana use is not correlated with maintenance of Body Mass Index in ALS patients. Abstract Following legalization, Medical Marijuana (MM), has been used to treat the symptoms of Amyotrophic Lateral Sclerosis (ALS), yet data regarding Medical Marijuana's efficacy is lacking. Thus, we conducted a retrospective cohort study to assess Medical Marijuana's impact on ALS symptoms and progression. We reviewed the...